a Department of Pathology , Anyang Tumor Hospital , Anyang , Henan , China.
b Department of Pulmonary Medicine , The First Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Cancer Biol Ther. 2017 Sep 2;18(9):676-680. doi: 10.1080/15384047.2017.1360440.
Rhabdomyosarcoma (RMS) is an uncommon type of soft-tissue malignancy which mainly influences children. RMS rarely occurs in breast and little of the clinical behavior and treatment strategies were reported. Here, we describe a case of adult female patient with breast RMS. A 34-years-old Chinese woman visited to our hospital complaining palpable mass in her left breast. Seven months ago, the patient was diagnosed as lymphocytic mastitis and received surgical excision in the left breast. Five months later, she noticed a palpable mass again in the left breast. Ultrasonography suspected a malignant lesion and a diagnosis of RMS was made after segmental mastectomy and immunohistochemical staining. Therapy consisted of mastectomy and following neoadjuvant chemotherapy. The patient has remained disease free 30 months post-operatively. We should consider RMS when we see a breast mass. Tissue biopsy and immunohistochemical staining are recommended for diagnosis of RMS in young women. Oncologists should take immediate and active treatment on RMS.
横纹肌肉瘤（RMS）是一种罕见的软组织恶性肿瘤，主要影响儿童。RMS 在乳房中很少见，报道的临床行为和治疗策略也很少。在这里，我们描述了一例成年女性乳房 RMS 的病例。一位 34 岁的中国女性因左乳房可触及肿块就诊于我院。7 个月前，该患者被诊断为淋巴细胞性乳腺炎，并接受了左乳房的手术切除。5 个月后，她再次发现左乳房可触及肿块。超声怀疑为恶性病变，经节段性乳房切除术和免疫组织化学染色诊断为 RMS。治疗包括乳房切除术和随后的新辅助化疗。患者术后 30 个月无病生存。当我们看到乳房肿块时，应考虑 RMS。对于年轻女性，建议进行组织活检和免疫组织化学染色以诊断 RMS。肿瘤学家应立即对 RMS 进行积极治疗。
