Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Retina. 2018 Oct;38(10):2051-2055. doi: 10.1097/IAE.0000000000001806.
The authors evaluated surgical outcomes in eyes with extremely high myopia for macular hole (MH) without retinal detachment.
In this retrospective study, 14 eyes with axial lengths of ≥30.0 mm underwent vitrectomy and internal limiting membrane (ILM) peeling with or without inverted ILM flap insertion for MH without retinal detachment (October 2009-June 2016). Outcome measures were MH closure confirmed by optical coherence tomography, best-corrected visual acuity, and complications.
The mean axial length was 30.69 ± 0.76 mm. The overall final closure rate was 85.7% (12/14 eyes); the mean follow-up was 17.29 (±20.20) months. Primary anatomical MH closure after 1 operation was achieved in three of eight eyes (37.5%) without an inverted ILM flap and was achieved in six of six eyes (100%) with inverted ILM flap insertion (P = 0.031). There was no reopening of MH during follow-up. Mean visual acuity improved significantly from 1.10 ± 0.43 logarithm of the minimum angle of resolution (Snellen equivalent, 20/254) to 0.84 ± 0.50 logarithm of the minimum angle of resolution (Snellen equivalent, 20/138) (P = 0.046; 2-tailed, paired t-test). Only 1 eye developed an MH-associated retinal detachment 4.5 years after previously failed MH surgery; reattachment was achieved after a second operation.
Patients with extremely high myopia obtained anatomical and functional improvements from MH surgery; inverted ILM flap insertion achieved significantly higher primary success rates in MH closure.
评估无视网膜脱离的特高度近视黄斑裂孔(MH)患者的手术效果。
在这项回顾性研究中,14 只眼轴长度≥30.0mm 的患者因无视网膜脱离的 MH 接受了玻璃体切除术和内界膜(ILM)剥除术,其中部分患者还进行了反转 ILM 瓣插入术(2009 年 10 月至 2016 年 6 月)。观察指标包括光学相干断层扫描(OCT)确认的 MH 闭合、最佳矫正视力和并发症。
平均眼轴长度为 30.69±0.76mm。总的最终闭合率为 85.7%(14 只眼中的 12 只);平均随访时间为 17.29±20.20 个月。8 只眼中 3 只(37.5%)未行反转 ILM 瓣插入术的眼和 6 只(100%)行反转 ILM 瓣插入术的眼在一次手术后即刻达到 MH 解剖学闭合(P=0.031)。在随访期间,MH 无再裂孔。平均视力从 1.10±0.43 视力对数(最小分辨角对数,20/254)显著提高至 0.84±0.50 视力对数(最小分辨角对数,20/138)(P=0.046;双侧,配对 t 检验)。仅有 1 只眼在先前失败的 MH 手术后 4.5 年出现 MH 相关视网膜脱离,再次手术后视网膜复位。
特高度近视患者行 MH 手术后获得了解剖学和功能改善;反转 ILM 瓣插入术可显著提高 MH 闭合的初始成功率。