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高度近视黄斑裂孔未脱离视网膜的手术结果。

SURGICAL OUTCOMES IN EYES WITH EXTREMELY HIGH MYOPIA FOR MACULAR HOLE WITHOUT RETINAL DETACHMENT.

机构信息

Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

School of Medicine, National Yang-Ming University, Taipei, Taiwan.

出版信息

Retina. 2018 Oct;38(10):2051-2055. doi: 10.1097/IAE.0000000000001806.

Abstract

PURPOSE

The authors evaluated surgical outcomes in eyes with extremely high myopia for macular hole (MH) without retinal detachment.

METHODS

In this retrospective study, 14 eyes with axial lengths of ≥30.0 mm underwent vitrectomy and internal limiting membrane (ILM) peeling with or without inverted ILM flap insertion for MH without retinal detachment (October 2009-June 2016). Outcome measures were MH closure confirmed by optical coherence tomography, best-corrected visual acuity, and complications.

RESULTS

The mean axial length was 30.69 ± 0.76 mm. The overall final closure rate was 85.7% (12/14 eyes); the mean follow-up was 17.29 (±20.20) months. Primary anatomical MH closure after 1 operation was achieved in three of eight eyes (37.5%) without an inverted ILM flap and was achieved in six of six eyes (100%) with inverted ILM flap insertion (P = 0.031). There was no reopening of MH during follow-up. Mean visual acuity improved significantly from 1.10 ± 0.43 logarithm of the minimum angle of resolution (Snellen equivalent, 20/254) to 0.84 ± 0.50 logarithm of the minimum angle of resolution (Snellen equivalent, 20/138) (P = 0.046; 2-tailed, paired t-test). Only 1 eye developed an MH-associated retinal detachment 4.5 years after previously failed MH surgery; reattachment was achieved after a second operation.

CONCLUSION

Patients with extremely high myopia obtained anatomical and functional improvements from MH surgery; inverted ILM flap insertion achieved significantly higher primary success rates in MH closure.

摘要

目的

评估无视网膜脱离的特高度近视黄斑裂孔(MH)患者的手术效果。

方法

在这项回顾性研究中,14 只眼轴长度≥30.0mm 的患者因无视网膜脱离的 MH 接受了玻璃体切除术和内界膜(ILM)剥除术,其中部分患者还进行了反转 ILM 瓣插入术(2009 年 10 月至 2016 年 6 月)。观察指标包括光学相干断层扫描(OCT)确认的 MH 闭合、最佳矫正视力和并发症。

结果

平均眼轴长度为 30.69±0.76mm。总的最终闭合率为 85.7%(14 只眼中的 12 只);平均随访时间为 17.29±20.20 个月。8 只眼中 3 只(37.5%)未行反转 ILM 瓣插入术的眼和 6 只(100%)行反转 ILM 瓣插入术的眼在一次手术后即刻达到 MH 解剖学闭合(P=0.031)。在随访期间,MH 无再裂孔。平均视力从 1.10±0.43 视力对数(最小分辨角对数,20/254)显著提高至 0.84±0.50 视力对数(最小分辨角对数,20/138)(P=0.046;双侧,配对 t 检验)。仅有 1 只眼在先前失败的 MH 手术后 4.5 年出现 MH 相关视网膜脱离,再次手术后视网膜复位。

结论

特高度近视患者行 MH 手术后获得了解剖学和功能改善;反转 ILM 瓣插入术可显著提高 MH 闭合的初始成功率。

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