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对麻醉后的蝾螈(绿红东美螈)进行磷和氟核磁共振检查。

Phosphorus and fluorine NMR examination of the anesthetized newt (Notopthalamus viridescens).

作者信息

Burt C T, Roberts J, Lojeski E, Hitzig B M

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1986;85(2):409-12. doi: 10.1016/0742-8413(86)90217-3.

Abstract

We have examined newts by 19F-NMR using the anesthetic halothane as a probe and in another set of experiments taken 31P-NMR spectra under similar conditions. The spectra were recorded from the animal's tail. The water soluble 31P-NMR signals point to little difference between anesthetized and unanesthetized newts except for the potential disappearance of two pools of inorganic phosphate in the anesthetized animals. The 19F spectra show two anesthetic populations in the tail which the phosphorus spectra suggest arise from populations of halothane in muscle and in lipid.

摘要

我们使用麻醉剂氟烷作为探针,通过19F核磁共振对蝾螈进行了检测,并在另一组实验中,于类似条件下采集了31P核磁共振光谱。光谱是从动物的尾巴记录的。水溶性31P核磁共振信号表明,麻醉和未麻醉的蝾螈之间差异不大,只是麻醉动物体内两池无机磷酸盐可能消失。19F光谱显示尾巴中有两个麻醉剂群体,磷光谱表明这两个群体分别来自肌肉和脂质中的氟烷群体。

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