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缅甸医生对病毒性肝炎和肝细胞癌管理的看法。

Physician perspectives on the management of viral hepatitis and hepatocellular carcinoma in Myanmar.

作者信息

Kim Yoona A, Trinh Sam, Thura Si, Kyi Khin Pyone, Lee Thomas, Sze Stan, Richards Adam, Aronsohn Andrew, Wong Grace L H, Tanaka Yasuhito, Dusheiko Geoffrey, Nguyen Mindie H

机构信息

Division of Gastroenterology and Hepatology, Stanford University, Stanford, California, United States of America.

Community Partners International, Berkeley, California, United States of America.

出版信息

PLoS One. 2017 Aug 10;12(8):e0181603. doi: 10.1371/journal.pone.0181603. eCollection 2017.

Abstract

BACKGROUND

In Myanmar, over five million people are infected with hepatitis B virus (HBV) and hepatitis C virus (HCV). Hepatitis has been a recent focus with the development of a National Strategic Plan on Hepatitis and plans to subsidize HCV treatment.

METHODS

During a two-day national liver disease symposium covering HCV, HBV, hepatocellular (HCC), and end-stage liver disease (ESLD), physician surveys were administered using the automated response system (ARS) to assess physician knowledge, perceptions of barriers to screening and treatment, and proposed solutions. Multivariate logistic regression was used to estimate odds ratio (OR) relating demography and practice factors with higher provider knowledge and improvement.

RESULTS

One hundred two physicians attending from various specialty areas (31.0% specializing in gastroenterology/hepatology and/or infectious disease) were of mixed gender (46.8% male), were younger than or equal to 40 years old (51.1% 20 to 40 years), had less experience (61.6% with ≤10 years of medical practice), were from the metropolitan area of Yangon (72.1%), and saw <10 liver disease patients per week (74.3%). The majority of physicians were not comfortable with treating or managing patients with liver disease. The post-test scores demonstrated an improvement in liver disease knowledge (9.0% ± 27.0) compared to the baseline pre-test scores; no variables were associated with significant improvement in hepatitis knowledge. Physicians identified the cost of diagnostic blood tests and treatment as the most significant barrier to treatment. Top solutions proposed were universal screening policies (46%), removal of financial barriers for treatment (29%), patient education (14%) and provider education (11%).

CONCLUSIONS

Physician knowledge improved after this symposium, and many other needs were revealed by the physician input on barriers to care and their solutions. These survey results are important in guiding the next steps to improve liver disease management and future medical education efforts in Myanmar.

摘要

背景

在缅甸,超过500万人感染了乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)。随着国家肝炎战略计划的制定以及对丙型肝炎治疗进行补贴的计划,肝炎问题成为了近期的关注焦点。

方法

在为期两天的涵盖丙型肝炎、乙型肝炎、肝细胞癌(HCC)和终末期肝病(ESLD)的全国肝病研讨会上,使用自动应答系统(ARS)对医生进行调查,以评估医生的知识、对筛查和治疗障碍的看法以及提出的解决方案。采用多变量逻辑回归来估计人口统计学和实践因素与更高的医生知识水平及改善情况之间的比值比(OR)。

结果

来自各个专业领域的102名医生(31.0%专门从事胃肠病学/肝病学和/或传染病),性别混合(46.8%为男性),年龄小于或等于40岁(51.1%为20至40岁),经验较少(61.6%的医生医疗实践年限≤10年),来自仰光市区(72.1%),且每周诊治的肝病患者少于10名(74.3%)。大多数医生对治疗或管理肝病患者不太得心应手。与基线预测试分数相比,测试后分数显示肝病知识有改善(9.0%±27.0);没有变量与肝炎知识的显著改善相关。医生们认为诊断性血液检测和治疗的费用是治疗的最主要障碍。提出的首要解决方案是通用筛查政策(46%)、消除治疗的经济障碍(29%)、患者教育(14%)和医生教育(11%)。

结论

本次研讨会后医生的知识有所提高,医生们关于护理障碍及其解决方案的意见还揭示了许多其他需求。这些调查结果对于指导缅甸改善肝病管理的下一步措施以及未来的医学教育工作具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9674/5552252/cfe920ffee46/pone.0181603.g001.jpg

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