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老年高血压

Hypertension in the Older Adult.

作者信息

Setters Belinda, Holmes Holly M

机构信息

Department of Internal Medicine, Robley Rex VAMC, University of Louisville School of Medicine, 800 Zorn Avenue, 6 West - GEC #627, Louisville, KY 40206, USA; Inpatient Geriatrics, Department of Family & Geriatric Medicine, Robley Rex VAMC, University of Louisville School of Medicine, 800 Zorn Avenue, 6 West - GEC #627, Louisville, KY 40206, USA.

Geriatric & Palliative Medicine, Department of Internal Medicine, University of Texas Houston McGovern Medical School, 6431 Fannin, MBS 5.111, Houston, TX 77030, USA.

出版信息

Prim Care. 2017 Sep;44(3):529-539. doi: 10.1016/j.pop.2017.05.002.

Abstract

Hypertension is common among adults and is associated with significant morbidity and mortality and should be routinely addressed in primary care practice. Optimal blood pressure targets have evolved in the past decade with the release of large studies including older persons. However, controversy remains regarding the treatment of older and frail patients. The relationship between blood pressure treatment and falls or cognitive impairment is still an area of concern and debate. A strategy to address hypertension in older persons should consider an individual's fitness and the likelihood of adverse effects and worsening of conditions that adversely affect quality of life.

摘要

高血压在成年人中很常见,与严重的发病率和死亡率相关,在初级保健实践中应常规处理。随着包括老年人在内的大型研究的发表,最佳血压目标在过去十年中有所发展。然而,对于老年和体弱患者的治疗仍存在争议。血压治疗与跌倒或认知障碍之间的关系仍是一个令人关注和争论的领域。针对老年人高血压的治疗策略应考虑个体的健康状况以及对生活质量产生不利影响的不良反应和病情恶化的可能性。

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Characterizing Frailty Status in the Systolic Blood Pressure Intervention Trial.在收缩压干预试验中对衰弱状态进行特征描述。
J Gerontol A Biol Sci Med Sci. 2016 May;71(5):649-55. doi: 10.1093/gerona/glv228. Epub 2016 Jan 11.
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A Randomized Trial of Intensive versus Standard Blood-Pressure Control.强化与标准血压控制的随机试验
N Engl J Med. 2015 Nov 26;373(22):2103-16. doi: 10.1056/NEJMoa1511939. Epub 2015 Nov 9.

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