Zhang Cheng, Zhang Shuai, Zhu Lusheng, Wang Jinhua, Wang Jun, Zhou Tongtong
College of Resources and Environment, Key Lab of Agricultural Environment in Universities of Shandong, Shandong Agricultural University, Taian 271018, China.
Environ Pollut. 2017 Oct;229:887-895. doi: 10.1016/j.envpol.2017.07.055. Epub 2017 Aug 7.
Given their increasingly widespread application, the toxic effects of ionic liquids (ILs) have become the subject of significant attention in recent years. Therefore, the present study assessed the acute toxic effects of 1-alkyl-3-methylimidazolium nitrate ([Cmim]NO (n = 2, 4, 6, 8, 10, 12)) on Chlorella vulgaris and Daphnia magna. The sensitivity of the tested organism Daphnia magna and the investigated IL concentrations in water using high-performance liquid chromatography (HPLC) were also evaluated to demonstrate the reliability of the present study. The results illustrated that Daphnia magna is indeed sensitive to the reference toxicant and the investigated ILs were stable in the aquatic environment. The 50% effect concentration (EC) was used to represent the acute toxic effects on Chlorella vulgaris and Daphnia magna. With the increasing alkyl-chain lengths, the toxicity of the investigated ILs increased in both the test organisms. Accordingly, the alkyl-chain lengths can cause significantly toxic effects on aquatic organisms, and Daphnia magna are much more sensitive than Chlorella vulgaris to the imidazolium-based ILs used in the present study. Furthermore, the present study provides more information on the acute toxic effects of 1-alkyl-3-methylimidazolium nitrate.
鉴于离子液体（ILs）的应用日益广泛，近年来其毒性效应已成为备受关注的主题。因此，本研究评估了1-烷基-3-甲基咪唑鎓硝酸盐（[Cmim]NO，n = 2、4、6、8、10、12）对普通小球藻和大型溞的急性毒性效应。还评估了受试生物大型溞的敏感性以及使用高效液相色谱法（HPLC）测定的水中所研究的离子液体浓度，以证明本研究的可靠性。结果表明，大型溞确实对参考毒物敏感，且所研究的离子液体在水生环境中稳定。用50%效应浓度（EC）来表示对普通小球藻和大型溞的急性毒性效应。随着烷基链长度增加，所研究的离子液体在两种受试生物中的毒性均增加。因此，烷基链长度可对水生生物产生显著毒性效应，并且大型溞对本研究中使用的基于咪唑鎓的离子液体比普通小球藻更为敏感。此外，本研究提供了关于1-烷基-3-甲基咪唑鎓硝酸盐急性毒性效应的更多信息。
