Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Int J Antimicrob Agents. 2017 Dec;50(6):726-729. doi: 10.1016/j.ijantimicag.2017.08.008. Epub 2017 Aug 7.
Recipients of allogeneic haematopoietic stem cell transplantation (allo-HSCT) are severely immunocompromised and are at increased risk of infection. In this prospective, observational, single-centre study including 110 allo-HSCT recipients, the rate of Staphylococcus aureus colonisation was reduced from 11.8% to 0% (P <0.001) following peritransplant oral gut decontamination. No invasive S. aureus infections were observed.
异基因造血干细胞移植（allo-HSCT）受者的免疫功能严重受损，感染风险增加。在这项包括 110 例 allo-HSCT 受者的前瞻性、观察性、单中心研究中，移植前口腔肠道去污使金黄色葡萄球菌定植率从 11.8%降至 0%（P<0.001）。未观察到侵袭性金黄色葡萄球菌感染。
