Inserm, U995, Lille inflammation research international center (LIRIC), university of Lille, 59006 Lille, France.
Inserm, U995, Lille inflammation research international center (LIRIC), university of Lille, 59006 Lille, France.
Med Mal Infect. 2017 Nov;47(7):477-483. doi: 10.1016/j.medmal.2017.07.001. Epub 2017 Aug 7.
The main goal of this study was to determine the in vitro susceptibility of strains collected from marketed probiotics to antibiotics used to treat community-acquired infections.
The minimum inhibitory concentrations (MICs) of 16 antibiotics were determined using a gradient strip (E test) or the agar dilution method for fidaxomicin.
The probiotics demonstrated various antibiotic patterns. Bacterial probiotics are generally susceptible to most prescribed antibiotics orally administered, whereas yeast probiotics, such as Saccharomyces boulardii, are resistant.
Special attention must be paid to co-prescriptions of antibiotics and probiotics to ensure that the probiotic strain is not susceptible.
本研究的主要目的是确定从市售益生菌中分离的菌株对用于治疗社区获得性感染的抗生素的体外敏感性。
使用梯度条（E 试验）或琼脂稀释法测定 16 种抗生素的最小抑菌浓度（MIC），适用于 fidaxomicin。
益生菌表现出不同的抗生素模式。细菌益生菌通常对大多数口服给予的处方抗生素敏感，而酵母益生菌，如布拉氏酵母菌，是耐药的。
必须特别注意抗生素和益生菌的联合处方，以确保益生菌菌株不易受影响。
