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The Signaling Theory of Symptoms : An Evolutionary Explanation of the Placebo Effect.症状的信号理论:安慰剂效应的一种进化解释
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2
Open-label placebo treatment in chronic low back pain: a randomized controlled trial.慢性下腰痛的开放标签安慰剂治疗:一项随机对照试验。
Pain. 2016 Dec;157(12):2766-2772. doi: 10.1097/j.pain.0000000000000700.
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Placebo Effects and Informed Consent.安慰剂效应与知情同意。
Am J Bioeth. 2015;15(10):3-12. doi: 10.1080/15265161.2015.1074302.
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Classical conditioning of analgesic and hyperalgesic pain responses without conscious awareness.无意识状态下镇痛和痛觉过敏疼痛反应的经典条件作用。
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Placebo effect of medication cost in Parkinson disease: a randomized double-blind study.帕金森病中药物成本的安慰剂效应:一项随机双盲研究。
Neurology. 2015 Feb 24;84(8):794-802. doi: 10.1212/WNL.0000000000001282. Epub 2015 Jan 28.
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Placebo analgesia: a predictive coding perspective.安慰剂镇痛:预测编码视角。
Neuron. 2014 Mar 19;81(6):1223-1239. doi: 10.1016/j.neuron.2014.02.042.
7
Arthroscopic partial meniscectomy versus sham surgery for a degenerative meniscal tear.关节镜下半月板部分切除术与假手术治疗退行性半月板撕裂。
N Engl J Med. 2013 Dec 26;369(26):2515-24. doi: 10.1056/NEJMoa1305189.
8
Nonconscious activation of placebo and nocebo pain responses.安慰剂和反安慰剂疼痛反应的无意识激活。
Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15959-64. doi: 10.1073/pnas.1202056109. Epub 2012 Sep 10.
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The evolutionary psychology of healing: a human success story.治愈的进化心理学:一个人类的成功故事。
Curr Biol. 2012 Sep 11;22(17):R695-8. doi: 10.1016/j.cub.2012.06.018.
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A Bayesian account of 'hysteria'.关于“癔症”的贝叶斯解释。
Brain. 2012 Nov;135(Pt 11):3495-512. doi: 10.1093/brain/aws129. Epub 2012 May 28.

安慰剂效应的具身认知解释。

An enactive account of placebo effects.

作者信息

Ongaro Giulio, Ward Dave

机构信息

Department of Anthropology, London School of Economics, Houghton Street, London, WC2A 2AE UK.

Department of Philosophy, University of Edinburgh, Dugald Stewart Building, 3 Charles Street, Edinburgh, EH8 9AD UK.

出版信息

Biol Philos. 2017;32(4):507-533. doi: 10.1007/s10539-017-9572-4. Epub 2017 Apr 12.

DOI:10.1007/s10539-017-9572-4
PMID:28798505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5524854/
Abstract

Placebos are commonly defined as ineffective treatments. They are treatments that lack a known mechanism linking their properties to the properties of the condition on which treatment aims to intervene. Given this, the fact that placebos can have substantial therapeutic effects looks puzzling. The puzzle, we argue, arises from the relationship placebos present between culturally meaningful entities (such as treatments or therapies), our intentional relationship to the environment (such as implicit or explicit beliefs about a treatment's healing powers) and bodily effects (placebo responses). How can a mere attitude toward a treatment result in appropriate bodily changes? We argue that an 'enactive' conception of cognition accommodates and renders intelligible the phenomenon of placebo effects. Enactivism depicts an organism's adaptive bodily processes, its intentional directedness, and the meaningful properties of its environment as co-emergent aspects of a single dynamic system. In doing so it provides an account of the interrelations between mind, body and world that demystifies placebo effects.

摘要

安慰剂通常被定义为无效治疗。它们是缺乏一种已知机制将其特性与治疗旨在干预的病症特性联系起来的治疗方法。鉴于此,安慰剂能产生显著治疗效果这一事实看起来令人困惑。我们认为,这个谜题源于安慰剂在文化上有意义的实体(如治疗方法或疗法)、我们与环境的意向性关系(如对一种治疗的治愈能力的隐性或显性信念)和身体效应(安慰剂反应)之间呈现的关系。对一种治疗的仅仅一种态度怎么会导致适当的身体变化呢?我们认为,一种“生成性”的认知概念能够容纳并使安慰剂效应现象变得可理解。生成论将生物体的适应性身体过程、其意向指向性以及其环境的有意义特性描述为一个单一动态系统的共同涌现方面。这样做,它提供了一种对心、身和世界之间相互关系的解释,从而使安慰剂效应不再神秘。