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褪黑素摄入及其对人类健康的潜在生物钟影响。

Melatonin intake and potential chronobiological effects on human health.

机构信息

a Department of Nutrition and Health , Universidade Federal de Viçosa , Viçosa , Minas Gerais , Brazil.

出版信息

Crit Rev Food Sci Nutr. 2019;59(1):133-140. doi: 10.1080/10408398.2017.1360837. Epub 2017 Oct 16.

DOI:10.1080/10408398.2017.1360837
PMID:28799779
Abstract

Melatonin is an indolamine with a recognized chronobiotic role. In turn, the supplementation of melatonin through capsules has been shown to be efficient in the modulation of inflammatory markers, oxidative stress, as well as in the control of hypertension and metabolic syndrome. However, the science of nutrition is interested in the study of the food sources of this hormone and its possible therapeutic effects. Thus, this review aimed to identify and present scientific papers that quantified melatonin in foods and evaluated its application in intervention studies. In total, 278 studies were found, of which 17 were included in this review. The results show that meats, fish, eggs, cereals, tubers, oilseeds, mushrooms, fruits, vegetables, alcoholic and non-alcoholic beverages and dairy products had some items analyzed for their melatonin concentrations. The concentrations reported presented considerable amplitude among different foods and even within the same species, possibly due to differences in cultivation and different hormonal dosing techniques. Also, different concentrations of melatonin can be presented for the same food when submitted to processes such as cooking, roasting or fermentation. The intervention studies presented positive results regarding the consumption of foods rich in melatonin and clinical-metabolic indicators. However, in order to guide nutritional behavior, it is necessary to consult a composition table that makes melatonin concentrations available and considers the processes involved in the preparation of the food. With this table, it will be possible to analyze the real effect of habitual consumption of melatonin from food on health.

摘要

褪黑素是一种具有公认的生物钟作用的吲哚胺。反过来,通过胶囊补充褪黑素已被证明能有效调节炎症标志物、氧化应激,以及控制高血压和代谢综合征。然而,营养科学研究的兴趣在于研究这种激素的食物来源及其可能的治疗效果。因此,本综述旨在确定并介绍定量分析食物中褪黑素并评估其在干预研究中应用的科学论文。总共发现了 278 篇研究论文,其中 17 篇被纳入本综述。结果表明,肉类、鱼类、蛋类、谷物、块茎类、油籽、蘑菇、水果、蔬菜、酒精和非酒精饮料以及乳制品都有一些项目对其褪黑素浓度进行了分析。报告的浓度在不同食物之间甚至在同一物种内都有很大的差异,这可能是由于种植和不同激素剂量技术的差异所致。此外,同一种食物在经过烹饪、烘烤或发酵等过程后,可能会呈现出不同浓度的褪黑素。干预研究显示,食用富含褪黑素和临床代谢指标的食物具有积极的效果。然而,为了指导营养行为,有必要查阅一份成分表,该表提供褪黑素的浓度,并考虑到食物制备过程中涉及的因素。有了这个表,就可以分析习惯性地从食物中摄入褪黑素对健康的实际影响。

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