Suppr超能文献

越南海防市静脉注射海洛因的情况:需要包括与使用甲基苯丙胺相关干预措施在内的综合护理。

Intravenous heroin use in Haiphong, Vietnam: Need for comprehensive care including methamphetamine use-related interventions.

作者信息

Michel Laurent, Des Jarlais Don C, Duong Thi Huong, Khuat Thi Hai Oanh, Pham Minh Khuê, Peries Marianne, Vallo Roselyne, Nham Thi Tuyet Thanh, Hoang Thi Giang, Le Sao Mai, Feelemyer Jonathan, Vu Hai Vinh, Moles Jean-Pierre, Laureillard Didier, Nagot Nicolas

机构信息

CESP/Inserm1018, Pierre Nicole Centre, French Red Cross, 27 Pierre Nicole Street, 75005, Paris, France.

Mount Sinai Beth Israel, 39 Broadway 5th Floor Suite 530 New York, NY 10006, USA.

出版信息

Drug Alcohol Depend. 2017 Oct 1;179:198-204. doi: 10.1016/j.drugalcdep.2017.07.004. Epub 2017 Aug 2.

Abstract

BACKGROUND

The aim of this study was to describe patterns among people who inject drugs (PWID), risk-related behaviours and access to methadone treatment, in order to design a large-scale intervention aiming to end the HIV epidemic in Haiphong, Vietnam.

METHODS

A respondent-driven sampling (RDS) survey was first conducted to identify profiles of drug use and HIV risk-related behaviour among PWID. A sample of PWID was then included in a one-year cohort study to describe access to methadone treatment and associated factors.

RESULTS

Among the 603 patients enrolled in the RDS survey, 10% were female, all were injecting heroin and 24% were using methamphetamine, including 3 (0.5%) through injection. Different profiles of risk-related behaviours were identified, including one entailing high-risk sexual behaviour (n=37) and another involving drug-related high-risk practices (n=22). High-risk sexual activity was related to binge drinking and methamphetamine use. Among subjects with low sexual risk, sexual intercourse with a main partner with unknown serostatus was often unprotected. Among the 250 PWID included in the cohort, 55.2% initiated methadone treatment during the follow-up (versus 4.4% at RDS); methamphetamine use significantly increased. The factors associated with not being treated with methadone after 52 weeks were fewer injections per month and being a methamphetamine user at RDS.

CONCLUSION

Heroin is still the main drug injected in Haiphong. Methamphetamine use is increasing markedly and is associated with delay in methadone initiation. Drug-related risks are low but sexual risk behaviours are still present. Comprehensive approaches are needed in the short term.

摘要

背景

本研究旨在描述注射吸毒者(PWID)的模式、与风险相关的行为以及美沙酮治疗的可及性,以便设计一项大规模干预措施,旨在终结越南海防市的艾滋病毒流行。

方法

首先进行了一项应答驱动抽样(RDS)调查,以确定PWID中药物使用情况和与艾滋病毒风险相关行为的概况。然后,选取PWID样本纳入一项为期一年的队列研究,以描述美沙酮治疗的可及性及相关因素。

结果

在RDS调查纳入的603名患者中,10%为女性,均注射海洛因,24%使用甲基苯丙胺,其中3人(0.5%)通过注射使用。识别出不同的与风险相关行为概况,包括一种涉及高风险性行为(n = 37),另一种涉及与毒品相关的高风险行为(n = 22)。高风险性行为与暴饮和使用甲基苯丙胺有关。在性风险较低的受试者中,与血清学状态不明的主要伴侣发生性行为时往往未采取保护措施。在队列纳入的250名PWID中,55.2%在随访期间开始接受美沙酮治疗(而在RDS时为4.4%);甲基苯丙胺的使用显著增加。52周后未接受美沙酮治疗的相关因素为每月注射次数较少以及在RDS时为甲基苯丙胺使用者。

结论

海洛因仍是海防市主要注射的毒品。甲基苯丙胺的使用显著增加,且与美沙酮起始延迟有关。与毒品相关的风险较低,但性风险行为仍然存在。短期内需要采取综合方法。

相似文献

引用本文的文献

本文引用的文献

5
Alcohol and drinking cultures in Vietnam: A review.越南的酒精与饮酒文化:综述
Drug Alcohol Depend. 2016 Feb 1;159:1-8. doi: 10.1016/j.drugalcdep.2015.10.030. Epub 2015 Nov 10.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验