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J Int AIDS Soc. 2016 Jul 18;19(4 Suppl 3):20879. doi: 10.7448/IAS.19.4.20879. eCollection 2016.
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Integrated respondent-driven sampling and peer support for persons who inject drugs in Haiphong, Vietnam: a case study with implications for interventions.越南海防市针对注射吸毒者的综合应答驱动抽样与同伴支持:一项对干预措施有启示意义的案例研究
AIDS Care. 2016 Oct;28(10):1312-5. doi: 10.1080/09540121.2016.1178698. Epub 2016 May 13.
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Drug addiction stigma in relation to methadone maintenance treatment by different service delivery models in Vietnam.越南不同服务提供模式下与美沙酮维持治疗相关的药物成瘾污名化问题。
BMC Public Health. 2016 Mar 8;16:238. doi: 10.1186/s12889-016-2897-0.
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Alcohol abuse increases the risk of HIV infection and diminishes health status of clients attending HIV testing services in Vietnam.酗酒会增加感染艾滋病毒的风险,并降低越南接受艾滋病毒检测服务的客户的健康状况。
Harm Reduct J. 2016 Feb 16;13:6. doi: 10.1186/s12954-016-0096-z.
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Alcohol and drinking cultures in Vietnam: A review.越南的酒精与饮酒文化:综述
Drug Alcohol Depend. 2016 Feb 1;159:1-8. doi: 10.1016/j.drugalcdep.2015.10.030. Epub 2015 Nov 10.
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Community pharmacy services for people with drug problems over two decades in Scotland: Implications for future development.二十多年来苏格兰为有药物问题的人提供的社区药房服务:对未来发展的启示。
Int J Drug Policy. 2016 Jan;27:105-12. doi: 10.1016/j.drugpo.2015.11.006. Epub 2015 Nov 27.
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Substance Use, Depression and Sociodemographic Determinants of HIV Sexual Risk Behavior in Outpatient Substance Abuse Treatment Patients.门诊药物滥用治疗患者中物质使用、抑郁与艾滋病毒性风险行为的社会人口学决定因素
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Preference of methadone maintenance patients for the integrative and decentralized service delivery models in Vietnam.越南美沙酮维持治疗患者对综合和分散式服务提供模式的偏好。
Harm Reduct J. 2015 Sep 17;12:29. doi: 10.1186/s12954-015-0063-0.
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Cessation of injecting drug use: The effects of health service utilisation, drug use and demographic factors.停止注射吸毒:卫生服务利用、吸毒及人口因素的影响
Drug Alcohol Depend. 2015 Sep 1;154:208-13. doi: 10.1016/j.drugalcdep.2015.06.037. Epub 2015 Jun 30.
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Alcohol Use Predicts Sexual Decision-Making: A Systematic Review and Meta-Analysis of the Experimental Literature.饮酒行为可预测性决策:对实验文献的系统评价与荟萃分析
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越南海防市静脉注射海洛因的情况:需要包括与使用甲基苯丙胺相关干预措施在内的综合护理。

Intravenous heroin use in Haiphong, Vietnam: Need for comprehensive care including methamphetamine use-related interventions.

作者信息

Michel Laurent, Des Jarlais Don C, Duong Thi Huong, Khuat Thi Hai Oanh, Pham Minh Khuê, Peries Marianne, Vallo Roselyne, Nham Thi Tuyet Thanh, Hoang Thi Giang, Le Sao Mai, Feelemyer Jonathan, Vu Hai Vinh, Moles Jean-Pierre, Laureillard Didier, Nagot Nicolas

机构信息

CESP/Inserm1018, Pierre Nicole Centre, French Red Cross, 27 Pierre Nicole Street, 75005, Paris, France.

Mount Sinai Beth Israel, 39 Broadway 5th Floor Suite 530 New York, NY 10006, USA.

出版信息

Drug Alcohol Depend. 2017 Oct 1;179:198-204. doi: 10.1016/j.drugalcdep.2017.07.004. Epub 2017 Aug 2.

DOI:10.1016/j.drugalcdep.2017.07.004
PMID:28800503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5911921/
Abstract

BACKGROUND

The aim of this study was to describe patterns among people who inject drugs (PWID), risk-related behaviours and access to methadone treatment, in order to design a large-scale intervention aiming to end the HIV epidemic in Haiphong, Vietnam.

METHODS

A respondent-driven sampling (RDS) survey was first conducted to identify profiles of drug use and HIV risk-related behaviour among PWID. A sample of PWID was then included in a one-year cohort study to describe access to methadone treatment and associated factors.

RESULTS

Among the 603 patients enrolled in the RDS survey, 10% were female, all were injecting heroin and 24% were using methamphetamine, including 3 (0.5%) through injection. Different profiles of risk-related behaviours were identified, including one entailing high-risk sexual behaviour (n=37) and another involving drug-related high-risk practices (n=22). High-risk sexual activity was related to binge drinking and methamphetamine use. Among subjects with low sexual risk, sexual intercourse with a main partner with unknown serostatus was often unprotected. Among the 250 PWID included in the cohort, 55.2% initiated methadone treatment during the follow-up (versus 4.4% at RDS); methamphetamine use significantly increased. The factors associated with not being treated with methadone after 52 weeks were fewer injections per month and being a methamphetamine user at RDS.

CONCLUSION

Heroin is still the main drug injected in Haiphong. Methamphetamine use is increasing markedly and is associated with delay in methadone initiation. Drug-related risks are low but sexual risk behaviours are still present. Comprehensive approaches are needed in the short term.

摘要

背景

本研究旨在描述注射吸毒者(PWID)的模式、与风险相关的行为以及美沙酮治疗的可及性,以便设计一项大规模干预措施,旨在终结越南海防市的艾滋病毒流行。

方法

首先进行了一项应答驱动抽样(RDS)调查,以确定PWID中药物使用情况和与艾滋病毒风险相关行为的概况。然后,选取PWID样本纳入一项为期一年的队列研究,以描述美沙酮治疗的可及性及相关因素。

结果

在RDS调查纳入的603名患者中,10%为女性,均注射海洛因,24%使用甲基苯丙胺,其中3人(0.5%)通过注射使用。识别出不同的与风险相关行为概况,包括一种涉及高风险性行为(n = 37),另一种涉及与毒品相关的高风险行为(n = 22)。高风险性行为与暴饮和使用甲基苯丙胺有关。在性风险较低的受试者中,与血清学状态不明的主要伴侣发生性行为时往往未采取保护措施。在队列纳入的250名PWID中,55.2%在随访期间开始接受美沙酮治疗(而在RDS时为4.4%);甲基苯丙胺的使用显著增加。52周后未接受美沙酮治疗的相关因素为每月注射次数较少以及在RDS时为甲基苯丙胺使用者。

结论

海洛因仍是海防市主要注射的毒品。甲基苯丙胺的使用显著增加,且与美沙酮起始延迟有关。与毒品相关的风险较低,但性风险行为仍然存在。短期内需要采取综合方法。