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孤立性斜坡转移:肾细胞癌的一种罕见表现。

Isolated clival metastasis: a rare presentation of renal cell carcinoma.

作者信息

Mani Anil, Yadav Priyank, Paliwal Vimal Kumar, Lal Hira

机构信息

Department of Urology and Renal Transplant, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

出版信息

BMJ Case Rep. 2017 Aug 11;2017:bcr-2017-221570. doi: 10.1136/bcr-2017-221570.

Abstract

Renal cell carcinoma accounts for 3% of all adult malignancies. Usual sites of metastasis are lymph nodes, lungs, bone, liver and brain. We describe a patient who presented with complaints of holocranial headache and diplopia. MRI of the head showed a clival-based lesion with associated bony erosion. With suspicion of a metastatic lesion, an ultrasonogram of the abdomen was done which showed a left renal mass that enhanced on contrast-enhanced CT. There were no other metastatic foci. Patient underwent radiotherapy for the clival lesion. This case report emphasises on the evaluation of clival lesion with cranial neuropathies for a possibility of a renal primary tumour.

摘要

肾细胞癌占所有成人恶性肿瘤的3%。常见转移部位为淋巴结、肺、骨、肝和脑。我们描述了一名出现全颅头痛和复视症状的患者。头部MRI显示一个位于斜坡的病变,并伴有骨质侵蚀。由于怀疑是转移性病变,遂进行了腹部超声检查,结果显示左肾有一个肿块,在增强CT上有强化。没有其他转移灶。患者接受了针对斜坡病变的放射治疗。本病例报告强调了对伴有颅神经病变的斜坡病变进行评估,以排查肾原发性肿瘤的可能性。

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本文引用的文献

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Metastatic disease to the clivus mimicking clival chordomas.模仿斜坡脊索瘤的斜坡转移性疾病。
J Neurol Surg B Skull Base. 2013 Oct;74(5):292-9. doi: 10.1055/s-0033-1348027. Epub 2013 Jun 26.
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Brain metastasis from renal cell carcinoma.肾细胞癌脑转移
Prog Neurol Surg. 2012;25:163-75. doi: 10.1159/000331190. Epub 2012 Jan 6.

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