Okudo Jerome, Anusim Nwabundo
School of Public Health, University of Texas, 1200 Pressler Street, Houston, TX 77030, USA.
Department of Medicine, Saint Joseph Regional Medical Center, 5215 Holy Cross Parkway, Mishawaka, IN 46545, USA.
Case Rep Neurol Med. 2016;2016:9184501. doi: 10.1155/2016/9184501. Epub 2016 Mar 15.
Renal cell carcinoma (RCC) has unusual presentation affecting elderly males with a smoking history. The incidence of RCC varies while the incidence of spread of RCC to the clivus is rare. The typicality of RCC presentation includes hematuria, flank pain, and a palpable flank mass; however, RCC can also present with clival metastasis. The unique path of the abducens nerve in the clivus makes it susceptible to damage in metastasis. We report a case of a 54-year-old African American female that was evaluated for back pain, weakness, numbness, and tingling of bilateral lower extremities and subsequently disconjugate gaze and diplopia. Brain MRI confirmed metastasis to the clivus. She was started on radiotherapy and was planned for chemotherapy and transfer to a nursing home. When a patient presents with sudden unusual cranial nerve pathology, the possibility of metastatic RCC should be sought.
肾细胞癌（RCC）具有不寻常的临床表现，影响有吸烟史的老年男性。RCC的发病率各不相同，而RCC扩散至斜坡的情况罕见。RCC的典型表现包括血尿、胁腹痛和可触及的胁腹肿块；然而，RCC也可表现为斜坡转移。展神经在斜坡走行独特，使其在转移时易受损伤。我们报告一例54岁非裔美国女性，因背痛、双侧下肢无力、麻木和刺痛接受评估，随后出现眼球运动分离和复视。脑部磁共振成像（MRI）证实斜坡转移。她开始接受放疗，并计划进行化疗，之后转至疗养院。当患者突然出现不寻常的颅神经病变时，应考虑转移性RCC的可能性。
