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偏头痛或紧张型头痛患者的非药物自我管理:一项包括干预成分分析的系统评价

Non-pharmacological self-management for people living with migraine or tension-type headache: a systematic review including analysis of intervention components.

作者信息

Probyn Katrin, Bowers Hannah, Mistry Dipesh, Caldwell Fiona, Underwood Martin, Patel Shilpa, Sandhu Harbinder Kaur, Matharu Manjit, Pincus Tamar

机构信息

Department of Psychology, Royal Holloway University of London, Egham, Surrey, UK.

Clinical Trials Unit, Warwick Medical School, Warwick University, Coventry, UK.

出版信息

BMJ Open. 2017 Aug 11;7(8):e016670. doi: 10.1136/bmjopen-2017-016670.

Abstract

OBJECTIVES

To assess the effect of non-pharmacological self-management interventions against usual care, and to explore different components and delivery methods within those interventions PARTICIPANTS: People living with migraine and/or tension-type headache INTERVENTIONS: Non-pharmacological educational or psychological self-management interventions; excluding biofeedback and physical therapy.We assessed the overall effectiveness against usual care on headache frequency, pain intensity, mood, headache-related disability, quality of life and medication consumption in meta-analysis.We also provide preliminary evidence on the effectiveness of intervention components and delivery methods.

RESULTS

We found a small overall effect for the superiority of self-management interventions over usual care, with a standardised mean difference (SMD) of -0.36 (-0.45 to -0.26) for pain intensity; -0.32 (-0.42 to -0.22) for headache-related disability, 0.32 (0.20 to 0.45) for quality of life and a moderate effect on mood (SMD=0.53 (-0.66 to -0.40)). We did not find an effect on headache frequency (SMD=-0.07 (-0.22 to 0.08)).Assessment of components and characteristics suggests a larger effect on pain intensity in interventions that included explicit educational components (-0.51 (-0.68 to -0.34) vs -0.28 (-0.40 to -0.16)); mindfulness components (-0.50 (-0.82 to -0.18) vs 0.34 (-0.44 to -0.24)) and in interventions delivered in groups vs one-to-one delivery (0.56 (-0.72 to -0.40) vs -0.39 (-0.52 to -0.27)) and larger effects on mood in interventions including a cognitive-behavioural therapy (CBT) component with an SMD of -0.72 (-0.93 to -0.51) compared with those without CBT -0.41 (-0.58 to -0.24).

CONCLUSION

Overall we found that self-management interventions for migraine and tension-type headache are more effective than usual care in reducing pain intensity, mood and headache-related disability, but have no effect on headache frequency. Preliminary findings also suggest that including CBT, mindfulness and educational components in interventions, and delivery in groups may increase effectiveness.

TRIAL REGISTRATION NUMBER

PROSPERO 2016:CRD42016041291.

摘要

目的

评估非药物自我管理干预措施相对于常规护理的效果,并探究这些干预措施中的不同组成部分和实施方法。

参与者

偏头痛和/或紧张型头痛患者

干预措施

非药物教育或心理自我管理干预措施;不包括生物反馈和物理治疗。我们在荟萃分析中评估了相对于常规护理在头痛频率、疼痛强度、情绪、头痛相关残疾、生活质量和药物消耗方面的总体效果。我们还提供了关于干预措施组成部分和实施方法有效性的初步证据。

结果

我们发现自我管理干预措施总体上略优于常规护理,疼痛强度的标准化均数差(SMD)为-0.36(-0.45至-0.26);头痛相关残疾为-0.32(-0.42至-0.22),生活质量为0.32(0.20至0.45),对情绪有中等程度影响(SMD = 0.53(-0.66至-0.40))。我们未发现对头痛频率有影响(SMD = -0.07(-0.22至0.08))。对组成部分和特征的评估表明,在包括明确教育成分的干预措施中对疼痛强度影响更大(-0.51(-0.68至-0.34)对-0.28(-0.40至-0.16));正念成分(-0.50(-0.82至-0.18)对0.34(-0.44至-0.24)),以及在团体实施的干预措施与一对一实施相比(0.56(-0.72至-0.40)对-0.39(-0.52至-0.27)),在包括认知行为疗法(CBT)成分的干预措施中对情绪影响更大,其SMD为-0.72(-0.93至-0.51),而没有CBT的为-0.41(-0.58至-0.24)。

结论

总体而言,我们发现偏头痛和紧张型头痛的自我管理干预措施在减轻疼痛强度、改善情绪和头痛相关残疾方面比常规护理更有效,但对头痛频率没有影响。初步研究结果还表明,在干预措施中纳入CBT、正念和教育成分以及团体实施可能会提高有效性。

试验注册号

PROSPERO 2016:CRD42016041291

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17f4/5629643/8e7ee4f92cf0/bmjopen-2017-016670f01.jpg

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