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与在低手术量医院进行的全膝关节置换术(TKA)相比,在高手术量医院进行的TKA翻修的可能性更小吗?

Are TKAs Performed in High-volume Hospitals Less Likely to Undergo Revision Than TKAs Performed in Low-volume Hospitals?

作者信息

Jeschke Elke, Citak Mustafa, Günster Christian, Matthias Halder Andreas, Heller Karl-Dieter, Malzahn Jürgen, Niethard Fritz Uwe, Schräder Peter, Zacher Josef, Gehrke Thorsten

机构信息

Research Institute of the Local Health Care Funds (AOK), Berlin, Germany.

Department of Orthopaedic Surgery, HELIOS ENDO-Klinik Hamburg, Holstenstraße 2, 22767, Hamburg, Germany.

出版信息

Clin Orthop Relat Res. 2017 Nov;475(11):2669-2674. doi: 10.1007/s11999-017-5463-x. Epub 2017 Aug 11.

Abstract

BACKGROUND

High-volume hospitals have achieved better outcomes for THAs and unicompartmental knee arthroplasties (UKAs). However, few studies have analyzed implant survival after primary TKA in high-volume centers.

QUESTIONS/PURPOSES: Is the risk of revision surgery higher when receiving a TKA in a low-volume hospital than in a high-volume hospital?

METHODS

Using nationwide billing data of the largest German healthcare insurer for inpatient hospital treatment, we identified 45,165 TKAs in 44,465 patients insured by Allgemeine Ortskrankenkasse who had undergone knee replacement surgery between January 2012 and December 2012. Revision rates were calculated at 1 and 2 years in all knees. The hospital volume was calculated using volume quintiles of the number of all knee arthroplasties performed in each center. We used multiple logistic regression to model the odds of revision surgery as a function of hospital volume. Age, sex, 31 comorbidities, and variables for socioeconomic status were included as independent variables in the model.

RESULTS

After controlling for socioeconomic factors, patient age, sex, and comorbidities, we found that having surgery in a high-volume hospital was associated with a decreased risk of having revision TKA within 2 years of the index procedure. The odds ratio for the 2-year revision was 1.6 (95% CI, 1.4-2.0; p < 0.001) for an annual hospital volume of 56 or fewer cases, 1.5 (95% CI, 1.3-1.7; p < 0.001) for 57 to 93 cases, 1.2 (95% CI, 1.0-1.3; p = 0.039) for 94 to 144 cases, and 1.1 (95% CI, 0.9-1.2; p = 0.319) for 145 to 251 cases compared with a hospital volume of 252 or more cases.

CONCLUSIONS

We found a clear association of higher risk for revision surgery when undergoing a TKA in a hospital where less than 145 arthroplasties per year were performed. The study results could help practitioners to guide potential patients in hospitals that perform more TKAs to reduce the overall revision and complication rates. Furthermore, this study underscores the importance of a minimum hospital threshold of arthroplasty cases per year to get permission to perform an arthroplasty.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

背景

高手术量医院在全髋关节置换术(THA)和单髁膝关节置换术(UKA)方面取得了更好的治疗效果。然而,很少有研究分析高手术量中心初次全膝关节置换术(TKA)后的植入物生存率。

问题/目的:在低手术量医院接受TKA的患者进行翻修手术的风险是否高于高手术量医院?

方法

利用德国最大的医疗保险机构提供的全国住院治疗计费数据,我们识别出了44465名参保于Allgemeine Ortskrankenkasse的患者在2012年1月至2012年12月期间接受的45165例膝关节置换手术。计算所有膝关节在1年和2年时的翻修率。通过各中心进行的所有膝关节置换手术数量的五分位数来计算医院手术量。我们使用多元逻辑回归模型来模拟翻修手术的几率作为医院手术量的函数。年龄、性别、31种合并症以及社会经济状况变量作为独立变量纳入模型。

结果

在控制了社会经济因素、患者年龄、性别和合并症后,我们发现,在高手术量医院进行手术与初次手术2年内TKA翻修风险降低相关。与每年手术量252例及以上的医院相比,每年手术量56例及以下的医院2年翻修的比值比为1.6(95%可信区间,1.4 - 2.0;p < 0.001),57至93例的为1.5(95%可信区间,1.3 - 1.7;p < 0.001),94至144例的为1.2(95%可信区间,1.0 - 1.3;p = 0.039),145至251例的为1.1(95%可信区间,0.9 - 1.2;p = 0.319)。

结论

我们发现,在每年进行少于145例关节置换手术的医院接受TKA时,翻修手术风险明显更高。研究结果可帮助从业者为更多进行TKA手术的医院中的潜在患者提供指导,以降低总体翻修率和并发症发生率。此外,本研究强调了每年进行关节置换手术的最低医院阈值对于获得进行关节置换手术许可的重要性。

证据水平

III级,治疗性研究。

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