Patel Aloka L, Panagos Patoula G, Silvestri Jean M
Department of Pediatrics, Rush University Children's Hospital, 1653 West Congress Parkway, Pavilion 353, Chicago, IL 60612, USA.
Department of Pediatrics, Rush University Children's Hospital, 1653 West Congress Parkway, Pavilion 361, Chicago, IL 60612, USA.
Clin Perinatol. 2017 Sep;44(3):683-700. doi: 10.1016/j.clp.2017.05.004. Epub 2017 Jul 5.
Necrotizing enterocolitis (NEC) is a multifactorial disease that occurs when multiple risk factors and/or stressors overlap, leading to profound inflammation and intestinal injury. Due to its multifactorial nature, there has been much uncertainty in identifying clear strategies for prevention of NEC. Despite these obstacles, the incidence of NEC has gradually been decreasing over the past 10 years, in part due to quality improvement (QI) initiatives to prevent NEC. Current QI strategies primarily target the various predisposing conditions. This article reviews the evidence on which QI interventions to prevent NEC have been based and provides examples of successful QI interventions.
坏死性小肠结肠炎（NEC）是一种多因素疾病，当多种风险因素和/或应激源相互重叠时就会发生，从而导致严重的炎症和肠道损伤。由于其多因素性质，在确定预防NEC的明确策略方面存在很大不确定性。尽管有这些障碍，但在过去10年中，NEC的发病率已逐渐下降，部分原因是预防NEC的质量改进（QI）举措。当前的QI策略主要针对各种易患因素。本文回顾了预防NEC所基于的QI干预措施的证据，并提供了成功的QI干预措施的实例。
