Boland Brigid S, Shergill Amandeep, Kaltenbach Tonya
Division of Gastroenterology, Department of Medicine, University of California, San Diego, CA, USA.
San Francisco Veterans Affairs Health Care System, San Francisco, CA, USA.
Curr Treat Options Gastroenterol. 2017 Sep;15(3):429-439. doi: 10.1007/s11938-017-0141-3.
There is a relative increase in the risk of colon cancer in patients with inflammatory bowel disease (IBD) affecting the colon, and endoscopic surveillance is advocated to mitigate this risk. The current standard practice is to survey this high-risk patient population using colonoscopy. Chromoendoscopy with targeted biopsies has emerged as the colonoscopy modality recommended by the major societies to optimize dysplasia detection. Studies over the past year support the improved yield from targeted as compared to random biopsies and improved dysplasia detection from chromoendoscopy as compared to white light endoscopy. Ongoing efforts should focus on the implementation of chromoendoscopy as the primary modality for colorectal cancer surveillance in IBD. Our review will describe current status and provide an update on the recent literature on surveillance colonoscopy in patients with IBD.
患有影响结肠的炎症性肠病(IBD)的患者患结肠癌的风险相对增加,因此提倡进行内镜监测以降低这种风险。目前的标准做法是使用结肠镜检查对这一高危患者群体进行检查。采用靶向活检的染色内镜已成为主要学会推荐的用于优化发育异常检测的结肠镜检查方式。过去一年的研究表明,与随机活检相比,靶向活检的检出率有所提高,与白光内镜相比,染色内镜对发育异常的检测有所改善。目前应致力于将染色内镜作为IBD患者结直肠癌监测的主要方式。我们的综述将描述当前状况,并提供关于IBD患者监测结肠镜检查的最新文献。