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加强临床前和临床中风恢复研究流程的一致性：中风恢复与康复圆桌会议转化工作组基于共识的核心建议

Enhancing the Alignment of the Preclinical and Clinical Stroke Recovery Research Pipeline: Consensus-Based Core Recommendations From the Stroke Recovery and Rehabilitation Roundtable Translational Working Group.

作者信息

Corbett Dale, Carmichael S Thomas, Murphy Timothy H, Jones Theresa A, Schwab Martin E, Jolkkonen Jukka, Clarkson Andrew N, Dancause Numa, Weiloch Tadeusz, Johansen-Berg Heidi, Nilsson Michael, McCullough Louise D, Joy Mary T

机构信息

1 Department of Cellular and Molecular Medicine, University of Ottawa, Canadian Partnership for Stroke Recovery, Ottawa, Canada.

2 Department of Neurology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, USA.

出版信息

Neurorehabil Neural Repair. 2017 Aug;31(8):699-707. doi: 10.1177/1545968317724285.

DOI:10.1177/1545968317724285
PMID:
28803530
Abstract

Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery.

摘要

与急性中风的研究相比，中风恢复的研究涉及不同的生物学和临床目标。针对中风恢复的临床前模型以及临床前研究与中风恢复临床试验的一致性，提出了相关指南。

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