1 Department of Cellular and Molecular Medicine, University of Ottawa, Canadian Partnership for Stroke Recovery, Ottawa, Canada.
2 Department of Neurology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, USA.
Int J Stroke. 2017 Jul;12(5):462-471. doi: 10.1177/1747493017711814.
Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery.
与急性中风研究相比,中风康复研究涉及不同的生物学和临床靶点。本文针对中风康复的临床前模型提出了一些建议,并为将临床前研究与中风康复临床试验相结合提供了指导。