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增强临床前和临床脑卒中康复研究管道的一致性：脑卒中康复和修复圆桌转化工作组基于共识的核心建议。

Enhancing the alignment of the preclinical and clinical stroke recovery research pipeline: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable translational working group.

机构信息

1 Department of Cellular and Molecular Medicine, University of Ottawa, Canadian Partnership for Stroke Recovery, Ottawa, Canada.

2 Department of Neurology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, USA.

出版信息

Int J Stroke. 2017 Jul;12(5):462-471. doi: 10.1177/1747493017711814.

DOI:10.1177/1747493017711814
PMID:28697710
Abstract

Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery.

摘要

与急性中风研究相比，中风康复研究涉及不同的生物学和临床靶点。本文针对中风康复的临床前模型提出了一些建议，并为将临床前研究与中风康复临床试验相结合提供了指导。

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