Department of Anaesthesiology, Hitachi Ltd., Hitachinaka General Hospital, Hitachinaka-shi, Japan.
Hitachinaka Medical Education and Research Center, University of Tsukuba Hospital, Hitachinaka-shi, Japan.
Anaesthesia. 2017 Nov;72(11):1344-1350. doi: 10.1111/anae.14026. Epub 2017 Aug 14.
We previously demonstrated that the gastric emptying time of different liquids with the same volume mainly depended on their energy content, regardless of differences in composition. In this crossover study, we investigated whether the same applies when soluble solid foods are ingested with water. Ten healthy volunteers ingested one of five test diets consisting of two test meals (Calorie Mate 100 and 200 kcal) and three test solutions (water and glucose solutions of 100 and 200 kcal), each given in a volume of 400 ml, and then underwent ultrasonography to measure the gastric antral cross-sectional area every 10 min for 120 min. The gastric emptying time was defined as the time for the antral cross-sectional area to revert to its initial value. When test diets with the same energy content were ingested, the gastric emptying curves were nearly identical, regardless of whether the original form was solid or liquid. The median (IQR[range]) gastric emptying times of Calorie Mate of 100 kcal with water vs. isocaloric glucose solution were 65 (60-78 [50-80]) vs. 65 (60-70 [50-80]) min (p = 0.58), and for Calorie Mate of 200 kcal with water vs. isocaloric glucose solution they were 100 (93-108 [90-120]) vs. 105 (90-110 [90-120]) min (p = 0.54). The median (IQR [range]) for water was 40 (30-40 [30-50]) min. Energy content may be a critical determinant of the gastric emptying time when ingesting soluble solid diets with water.
我们之前已经证明，相同体积的不同液体的胃排空时间主要取决于它们的能量含量，而与组成成分的差异无关。在这项交叉研究中，我们研究了当摄入与水混合的可溶性固体食物时是否同样适用。十名健康志愿者摄入了五种测试饮食中的一种，包括两种测试餐（Calorie Mate 100 和 200 卡路里）和三种测试溶液（水和 100 和 200 卡路里的葡萄糖溶液），每种饮食的体积均为 400 毫升，然后进行超声检查，以测量胃窦横截面积，每 10 分钟测量一次，共 120 分钟。胃排空时间定义为胃窦横截面积恢复到初始值的时间。当摄入具有相同能量含量的测试饮食时，无论原始形式是固体还是液体，胃排空曲线几乎相同。Calorie Mate 100 卡路里与水的胃排空时间中位数（IQR[范围]）为 65（60-78[50-80]）比等热量葡萄糖溶液为 65（60-70[50-80]）分钟（p=0.58），Calorie Mate 200 卡路里与水的胃排空时间中位数（IQR[范围]）为 100（93-108[90-120]）比等热量葡萄糖溶液为 105（90-110[90-120]）分钟（p=0.54）。水的中位数（IQR[范围]）为 40（30-40[30-50]）分钟。当摄入与水混合的可溶性固体饮食时，能量含量可能是胃排空时间的关键决定因素。
