Ivgi Inbal, Smidt Ami, Zaltsman Nathan, Ben-Gal Gilad, Beyth Nurit
Int J Prosthodont. 2017 September/October;30(5):471–473. doi: 10.11607/ijp.5336. Epub 2017 Aug 14.
Provisional restorations exhibit various degrees of microleakage when cemented. Incorporation of quaternized polyethyleneimine nanoparticles (QPEI) into provisional cements may be effective against bacteria in vivo.
Nine polymethylmethacrylate provisional restorations in human volunteers were evaluated after cementation with and without QPEI nanoparticles. Bacterial load in the provisional cement was assessed after 1 week of cementation.
The number of colony-forming units in the cement with QPEI was significantly lower (P < .05) than in the control cement.
The results of this in vivo study clearly indicate that provisional cement incorporating QPEI nanoparticles significantly reduces viable bacterial counts in the provisional cement in all patients.
临时修复体在粘结时会出现不同程度的微渗漏。将季铵化聚乙烯亚胺纳米颗粒（QPEI）加入临时粘结剂中可能在体内对细菌有效。
在9名人类志愿者中，对9个聚甲基丙烯酸甲酯临时修复体在粘结有无QPEI纳米颗粒的情况下进行评估。粘结1周后评估临时粘结剂中的细菌载量。
含QPEI的粘结剂中菌落形成单位数量显著低于对照粘结剂（P < .05）。
这项体内研究结果清楚地表明，含QPEI纳米颗粒的临时粘结剂能显著降低所有患者临时粘结剂中的活菌计数。
