Antibacterial Effect of Provisional Cements with Incorporated Polyethyleneimine Nanoparticles: An In Vivo Study.

PURPOSE

Provisional restorations exhibit various degrees of microleakage when cemented. Incorporation of quaternized polyethyleneimine nanoparticles (QPEI) into provisional cements may be effective against bacteria in vivo.

MATERIALS AND METHODS

Nine polymethylmethacrylate provisional restorations in human volunteers were evaluated after cementation with and without QPEI nanoparticles. Bacterial load in the provisional cement was assessed after 1 week of cementation.

RESULTS

The number of colony-forming units in the cement with QPEI was significantly lower (P < .05) than in the control cement.

CONCLUSION

The results of this in vivo study clearly indicate that provisional cement incorporating QPEI nanoparticles significantly reduces viable bacterial counts in the provisional cement in all patients.