Shodo R, Sato Y, Ota H, Horii A
Department of Head and Neck Surgery,Niigata Cancer Center Hospital,Niigata,Japan.
Department of Otolaryngology Head and Neck Surgery,Niigata University Graduate School of Medical and Dental Sciences,Niigata,Japan.
J Laryngol Otol. 2017 Nov;131(11):1026-1029. doi: 10.1017/S0022215117001748. Epub 2017 Aug 15.
Non-traumatic bone fractures in cancer patients are usually pathological fractures due to bone metastases. In head and neck cancer patients, clavicle stress fractures may occur as a result of atrophy of the trapezius muscle after neck dissection in which the accessory nerve becomes structurally or functionally damaged.
A 71-year-old man underwent modified radical neck dissection with accessory nerve preservation and post-operative radiotherapy for submandibular lymph node metastases of tongue cancer. Four weeks after the radiotherapy, a clavicle fracture, with osteomyelitis and abscess formation in the pectoralis major muscle, occurred. Unlike in simple stress fracture, long-term antibiotic administration and drainage surgery were required to suppress the inflammation.
As seen in the present patient, clavicle stress fractures may occur even after neck dissection in which the accessory nerve is preserved, and may be complicated by osteomyelitis and abscess formation owing to risk factors such as radiotherapy, tracheostomy and contiguous infection.
癌症患者的非创伤性骨折通常是由骨转移引起的病理性骨折。在头颈部癌症患者中,由于颈部清扫术后斜方肌萎缩,副神经在结构或功能上受损,可能会发生锁骨应力性骨折。
一名71岁男性因舌癌下颌下淋巴结转移接受了保留副神经的改良根治性颈部清扫术及术后放疗。放疗四周后,发生了锁骨骨折,并伴有胸大肌骨髓炎和脓肿形成。与单纯应力性骨折不同,需要长期使用抗生素并进行引流手术以控制炎症。
如本病例所示,即使在保留副神经的颈部清扫术后,也可能发生锁骨应力性骨折,并且由于放疗、气管切开术和邻近感染等危险因素,可能并发骨髓炎和脓肿形成。