Heisterberg L, Petersen K, Sørensen S S, Nielsen D
Int J Gynaecol Obstet. 1986 Oct;24(5):343-6. doi: 10.1016/0020-7292(86)90152-9.
In a double-blind controlled trial the efficacy of prophylactic metronidazole and pivampicillin to women with a history of pelvic inflammatory disease (PID) undergoing first-trimester abortion was assessed. Thirty-eight women received pivampicillin tablets 350 mg and 43 women metronidazole tablets 400 mg, given 1 h before and 4 and 8 h after the abortion. In the pivampicillin group 5 women (13.1%) and in the metronidazole group 8 women (18.6%) developed post-abortal PID, a non-significant difference (P greater than 0.05). The number of hospital days and amounts of antibiotics were not significantly different in the two treatment groups (all P-values greater than 0.05). Women with a history of PID were found to be at risk of contracting postabortal PID.
在一项双盲对照试验中，评估了预防性使用甲硝唑和匹氨西林对有盆腔炎（PID）病史且接受孕早期流产的女性的疗效。38名女性服用350毫克匹氨西林片，43名女性服用400毫克甲硝唑片，在流产前1小时以及流产后4小时和8小时给药。在匹氨西林组中，5名女性（13.1%）发生流产后PID，在甲硝唑组中，8名女性（18.6%）发生流产后PID，差异无统计学意义（P大于0.05）。两个治疗组的住院天数和抗生素用量差异均无统计学意义（所有P值均大于0.05）。有PID病史的女性被发现有发生流产后PID的风险。
