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手术治疗的脊柱转移瘤:预后评分有作用吗?

Surgically treated spinal metastases: Do prognostic scores have a role?

作者信息

Afsar Afifa, Qadeer Mohsin, Sharif Salman

机构信息

Department of Neurosurgery, Liaquat National Hospital and Medical College, Institute of Postgraduate Studies and Medical Sciences, Karachi, Pakistan.

出版信息

Surg Neurol Int. 2017 Jul 25;8:158. doi: 10.4103/sni.sni_72_17. eCollection 2017.

DOI:10.4103/sni.sni_72_17
PMID:28808607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5535510/
Abstract

BACKGROUND

The outcome for patients with metastatic disease in spine is difficult to predict. Multiple scoring systems were utilized in this study to determine their effectiveness in predicting long-term prognoses.

METHODS

A retrospective analysis of surgically treated patients of spinal metastasis was performed between 2005 and 2016. Data were collected prospectively during which 8 patients were lost to follow-up. Ultimately, data from 63 patients were reviewed. Treatment and prognoses were analyzed utilizing various scoring systems including the SINS, the Tomita, the modified Tokouhashi and Bauer scores.

RESULTS

Records of 63 patients, averaging 54 years of age, were analyzed. The Tomita score was applied in 44 patients, a modified Bauer score was studied in 49 patients, while SINS and modified Tokouhashi scores were calculated in all 63 patients. The hazard ratios for the Tomita score were 1, 0.030, 0.622, and 0.272, respectively. The hazard ratios for the modified Bauer scores were 1, 4.663, and 1.622, respectively. The Tokouhashi ratios were 1, 1.656, and 0.501, respectively. Of interest, the Tomita scores provided the highest statistical significance ( = 0.000) followed by the Bauer ( = 0.002) and Tokuhashi scores ( = 0.003). Notably, the SINS score showed no significant correlation in predicting patient survival.

CONCLUSION

For evaluating the metastatic spine disease, this study evaluated the prognostic efficacy of four widely used scores: the Tomita, score, the modified Tokouhashi and Bauer scores, and the SINS scores. The Tomita scores provided the highest statistical significance, followed by the Bauer, and Tokuhashi scores, while the SINS score showed no significant correlation in predicting patient survival.

摘要

背景

脊柱转移性疾病患者的预后难以预测。本研究采用多种评分系统来确定它们在预测长期预后方面的有效性。

方法

对2005年至2016年间接受手术治疗的脊柱转移瘤患者进行回顾性分析。前瞻性收集数据,期间有8例患者失访。最终,对63例患者的数据进行了审查。利用包括SINS、Tomita、改良Tokuhashi和Bauer评分在内的各种评分系统分析治疗和预后情况。

结果

分析了63例患者的记录,平均年龄54岁。44例患者应用了Tomita评分,49例患者研究了改良Bauer评分,而所有63例患者均计算了SINS和改良Tokuhashi评分。Tomita评分的风险比分别为1、0.030、0.622和0.272。改良Bauer评分的风险比分别为1、4.663和1.622。Tokuhashi评分的风险比分别为1、1.656和0.501。有趣的是,Tomita评分具有最高的统计学意义(P = 0.000),其次是Bauer评分(P = 0.002)和Tokuhashi评分(P = 0.003)。值得注意的是,SINS评分在预测患者生存方面无显著相关性。

结论

为评估脊柱转移性疾病,本研究评估了四种广泛使用的评分的预后效能:Tomita评分、改良Tokuhashi评分、Bauer评分和SINS评分。Tomita评分具有最高的统计学意义,其次是Bauer评分和Tokuhashi评分,而SINS评分在预测患者生存方面无显著相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/d63449c84481/SNI-8-158-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/1b7cffcdd81a/SNI-8-158-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/231d7bb0728f/SNI-8-158-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/da3affc15e63/SNI-8-158-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/47b0be85cc4a/SNI-8-158-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/1dda4c2c03f1/SNI-8-158-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/f0f762a1897a/SNI-8-158-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/d63449c84481/SNI-8-158-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/1b7cffcdd81a/SNI-8-158-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/231d7bb0728f/SNI-8-158-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/da3affc15e63/SNI-8-158-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/47b0be85cc4a/SNI-8-158-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/1dda4c2c03f1/SNI-8-158-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/f0f762a1897a/SNI-8-158-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f401/5535510/d63449c84481/SNI-8-158-g017.jpg

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Reliability of a spinal metastasis prognostic score to model 1-year survival.用于预测1年生存率的脊柱转移预后评分的可靠性。
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Analysis of the predictive role and new proposal for surgical strategies based on the modified Tomita and Tokuhashi scoring systems for spinal metastasis.
转移性脊柱肿瘤切除术后30天并发症及再入院率:单机构经验
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Can J Surg. 2014 Jun;57(3):188-93. doi: 10.1503/cjs.012013.
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Predictive value of seven preoperative prognostic scoring systems for spinal metastases.七种术前预后评分系统对脊柱转移瘤的预测价值
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Comparison of prognostic scores and surgical approaches to treat spinal metastatic tumors: a review of 57 cases.比较不同预后评分系统和手术入路治疗脊柱转移瘤的疗效:57 例回顾性研究。
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