Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China (mainland).
Department of Internal Medicine, Baotun Community Health Station, Houjie Township, Dongguan, Guangdong, China (mainland).
Med Sci Monit. 2017 Aug 15;23:3942-3951. doi: 10.12659/msm.902705.
BACKGROUND Functional dyspepsia (FD) refers to a group of upper gastrointestinal syndromes, subdivided into two types: postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS). The etiology of FD remains unclear; however, unhealthy dietary habit is one potential underlying cause. We aim to explore the association of poor dietary habits with FD and its subtypes. MATERIAL AND METHODS A validated epidemiological questionnaire was designed to investigate dietary habits and gastrointestinal syndromes. Citizens in the Baotun community of Dongguan were invited to complete the study questionnaire. All participants were asked to undergo a physical examination and a blinded physician interview. The study was conducted from June 2015 to June 2016. FD was diagnosed using ROME III criteria. The association between investigated dietary habits and dyspeptic symptoms were explored. RESULTS There were 1,304 adult residents recruited for the study survey; 165 residents had existing organic dyspepsia (OD), 203 residents were diagnosed with FD, and the other 936 participants, who were without dyspeptic symptoms or functional gastrointestinal diseases, were regarded as the control group. Subtype diagnosis indicated 61 participants had EPS, 66 participants had PDS, and 76 participants had coexisting EPS and PDS. Unhealthy dietary habits were more prevalent in the FD group than in the control groups (75.86% versus 37.50%; p<0.001). FD was found to be associated with irregular mealtime, dining out, fatty food, sweet food, and coffee (p<0.05). The impact of each dietary factor varied with FD subtypes. CONCLUSIONS Certain types of dietary habits were positively correlated with the prevalence of FD. FD subtypes showed relatively different associations with dietary factors.
功能性消化不良（FD）是一组上消化道综合征，分为餐后不适综合征（PDS）和上腹疼痛综合征（EPS）两种类型。FD 的病因尚不清楚；然而，不健康的饮食习惯是潜在的原因之一。我们旨在探讨不良饮食习惯与 FD 及其亚型的关系。
设计了一份经过验证的流行病学问卷，以调查饮食习惯和胃肠道综合征。邀请东莞宝屯社区的市民填写研究问卷。所有参与者都接受了体检和医生盲访。该研究于 2015 年 6 月至 2016 年 6 月进行。FD 采用罗马 III 标准诊断。探讨了所调查的饮食习惯与消化不良症状之间的关系。
共有 1304 名成年居民参加了研究调查；165 名居民有现有的器质性消化不良（OD），203 名居民被诊断为 FD，其余 936 名无消化不良症状或功能性胃肠道疾病的参与者被视为对照组。亚型诊断表明 61 名参与者有 EPS，66 名参与者有 PDS，76 名参与者有 EPS 和 PDS 共存。不健康的饮食习惯在 FD 组中比对照组更为普遍（75.86%比 37.50%；p<0.001）。FD 与不规律的进餐时间、外出就餐、油腻食物、甜食和咖啡有关（p<0.05）。每种饮食因素的影响因 FD 亚型而异。
某些类型的饮食习惯与 FD 的患病率呈正相关。FD 亚型与饮食因素的相关性存在差异。
