羟基脲诱发的二十甲横向黑甲：病例报告及文献复习

Twenty-Nail Transverse Melanonychia Induced by Hydroxyurea: Case Report and Review of the Literature.

作者信息

Osemwota Osamuede, Uhlemann John, Rubin Adam

出版信息

J Drugs Dermatol. 2017 Aug 1;16(8):814-815.

Abstract

Twenty-nail transverse melanonychia from hydroxyurea is a rare phenomenon, only reported four times previously. Here we describe a 51-year-old female who presented with 20-nail transverse melanonychia 3 months after initiating hydroxyurea therapy. Transverse melanonychia is a benign process but can cause patients significant distress, and thus is an entity with which dermatologists should recognize. We then review the cutaneous manifestations, differential diagnosis, and clinical considerations when evaluating patients with transverse melanonychia from hydroxyurea or other causes.

J Drugs Dermatol. 2017;16(8):814-815.

摘要

羟基脲所致的二十甲横形黑甲是一种罕见现象，此前仅报道过4次。在此，我们描述一名51岁女性，在开始羟基脲治疗3个月后出现二十甲横形黑甲。横形黑甲是一个良性过程，但会给患者带来极大困扰，因此皮肤科医生应认识这一病症。然后，我们回顾了在评估羟基脲或其他原因所致横形黑甲患者时的皮肤表现、鉴别诊断及临床注意事项。

《药物皮肤病学杂志》2017年；16(8):814 - 815。