新型流感 D 病毒：流行病学、病理学、进化和生物学特性。
Novel Influenza D virus: Epidemiology, pathology, evolution and biological characteristics.
机构信息
a Jiangsu Engineering Laboratory of Animal Immunology , Institute of Immunology and College of Veterinary Medicine, Nanjing Agricultural University , Nanjing , China.
b Key Laboratory of Zoonosis Prevention and Control of Guangdong Province and College of Veterinary Medicine , South China Agricultural University , Guangzhou , China.
出版信息
Virulence. 2017 Nov 17;8(8):1580-1591. doi: 10.1080/21505594.2017.1365216. Epub 2017 Aug 25.
Abstract
In 2011, a new virus was isolated from pigs with influenza-like symptoms and subsequently also from cattle, which are the main reservoir of the virus. It is similar to Influenza C virus (ICV), a (predominantly) human pathogen, causing respiratory disease in children. Since the virus is unable to reassort with ICV (and based on several other criteria as discussed in the text) it is now officially named as Influenzavirus D (IDV), a new genus of the Orthomyxoviridae. We summarize the epidemiology, pathology and evolution of IDV and its biological characteristics with emphasis on the only glycoprotein HEF. Based on the limited data available we finally consider whether IDV represent a public health threat.
摘要
2011 年，从出现流感样症状的猪中分离到一种新型病毒，随后也从牛中分离到这种病毒，牛是该病毒的主要宿主。它类似于流感 C 病毒（ICV），一种（主要）人类病原体，会导致儿童呼吸道疾病。由于该病毒不能与 ICV 重配（并且基于文本中讨论的其他几个标准），因此它现在被正式命名为流感病毒 D（IDV），这是正粘病毒科的一个新属。我们总结了 IDV 的流行病学、病理学和进化及其生物学特性，重点介绍了唯一的糖蛋白 HEF。根据现有有限的数据，我们最终考虑了 IDV 是否构成公共卫生威胁。
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