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即时检验的使用是否能提高国民保健服务(NHS)健康检查计划在初级医疗环境中的成本效益?一项成本最小化分析。

Does use of point-of-care testing improve cost-effectiveness of the NHS Health Check programme in the primary care setting? A cost-minimisation analysis.

作者信息

El-Osta Austen, Woringer Maria, Pizzo Elena, Verhoef Talitha, Dickie Claire, Ni Melody Z, Huddy Jeremy R, Soljak Michael, Hanna George B, Majeed Azeem

机构信息

Department of Primary Care and Public Health, Imperial College London, London W6 8RP, UK.

Department of Applied Health Research, University College London, London WC1E 7HB, UK.

出版信息

BMJ Open. 2017 Aug 15;7(8):e015494. doi: 10.1136/bmjopen-2016-015494.

Abstract

OBJECTIVE

To determine if use of point of care testing (POCT) is less costly than laboratory testing to the National Health Service (NHS) in delivering the NHS Health Check (NHSHC) programme in the primary care setting.

DESIGN

Observational study and theoretical mathematical model with microcosting approach.

SETTING

We collected data on NHSHC delivered at nine general practices (seven using POCT; two not using POCT).

PARTICIPANTS

We recruited nine general practices offering NHSHC and a pathology services laboratory in the same area.

METHODS

We conducted mathematical modelling with permutations in the following fields: provider type (healthcare assistant or nurse), type of test performed (total cholesterol with either lab fasting glucose or HbA1c), cost of consumables and variable uptake rates, including rate of non-response to invite letter and rate of missed [did not attend (DNA)] appointments. We calculated total expected cost (TEC) per 100 invites, number of NHSHC conducted per 100 invites and costs for completed NHSHC for laboratory and POCT-based pathways. A univariate and probabilistic sensitivity analysis was conducted to account for uncertainty in the input parameters.

MAIN OUTCOME MEASURES

We collected data on cost, volume and type of pathology services performed at seven general practices using POCT and a pathology services laboratory. We collected data on response to the NHSHC invitation letter and DNA rates from two general practices.

RESULTS

TEC of using POCT to deliver a routine NHSHC is lower than the laboratory-led pathway with savings of £29 per 100 invited patients up the point of cardiovascular disease risk score presentation. Use of POCT can deliver NHSHC in one sitting, whereas the laboratory pathway offers patients several opportunities to DNA appointment.

CONCLUSIONS

TEC of using POCT to deliver an NHSHC in the primary care setting is lower than the laboratory-led pathway. Using POCT minimises DNA rates associated with laboratory testing and enables completion of NHSHC in one sitting.

摘要

目的

确定在初级保健环境中实施国民健康检查(NHSHC)计划时,即时检验(POCT)对英国国家医疗服务体系(NHS)而言成本是否低于实验室检测。

设计

采用微观成本核算方法的观察性研究和理论数学模型。

设置

我们收集了在9家全科诊所(7家使用POCT;2家不使用POCT)开展的NHSHC的数据。

参与者

我们招募了9家提供NHSHC的全科诊所和同一地区的一家病理服务实验室。

方法

我们在以下领域进行了排列组合的数学建模:提供者类型(医疗保健助理或护士)、所进行的检测类型(总胆固醇与实验室空腹血糖或糖化血红蛋白)、耗材成本和可变接受率,包括对邀请信无回应率和错过[未就诊(DNA)]预约率。我们计算了每100次邀请的总预期成本(TEC)、每100次邀请进行的NHSHC数量以及基于实验室和POCT途径完成NHSHC的成本。进行了单变量和概率敏感性分析,以考虑输入参数的不确定性。

主要观察指标

我们收集了7家使用POCT的全科诊所和一家病理服务实验室进行的病理服务的成本、数量和类型的数据。我们收集了两家全科诊所对NHSHC邀请信的回应和DNA率的数据。

结果

使用POCT进行常规NHSHC的TEC低于实验室主导的途径,在心血管疾病风险评分呈现之前,每100名受邀患者可节省29英镑。使用POCT可以一次性完成NHSHC,而实验室途径为患者提供了多次错过预约的机会。

结论

在初级保健环境中使用POCT进行NHSHC的TEC低于实验室主导的途径。使用POCT可将与实验室检测相关的DNA率降至最低,并能一次性完成NHSHC。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cec/5724165/fdd0e6b0840f/bmjopen-2016-015494f01.jpg

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