Hayakawa Toyokazu, Nonaka Tetsuo, Mizoguchi Nobutaka, Hagiwara Yasuhito, Shibata Shino, Sakai Rika, Nakayama Norisuke, Yokose Tomoyuki, Nakayama Yuko
Department of Radiation Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, Yokohama, 241-8515, Kanagawa, Japan.
Department of Radiation Oncology, School of Medicine, Kitasato University, Sagamihara, Japan.
Clin J Gastroenterol. 2017 Oct;10(5):431-436. doi: 10.1007/s12328-017-0769-5. Epub 2017 Aug 16.
Extra-nodal mucosa-associated lymphoid tissue (MALT) lymphoma is frequently involved with the upper gastrointestinal tract, but rarely involved with the rectum. We report a case of rectal MALT lymphoma treated by radiotherapy (RT) alone. A 74-year-old woman with lower abdominal pain was diagnosed with MALT lymphoma by endoscopic mucosal resection (EMR). She was diagnosed as stage IE (Ann Arbor) MALT lymphoma by diagnostic work-up and review of EMR specimens. Definitive RT was performed with curative intent, totaling 30 Gy in 15 fractions. Complete response was confirmed by colonoscopy after RT with no progression observed at 5 years. Definitive RT is effective for rectal MALT lymphoma.
结外黏膜相关淋巴组织（MALT）淋巴瘤常累及上消化道，但很少累及直肠。我们报告一例仅接受放射治疗（RT）的直肠MALT淋巴瘤病例。一名74岁下腹痛女性经内镜黏膜切除术（EMR）诊断为MALT淋巴瘤。通过诊断性检查和对EMR标本的复查，她被诊断为Ann Arbor分期IE期MALT淋巴瘤。以治愈为目的进行了根治性放疗，共15次，总量30Gy。放疗后经结肠镜检查确认完全缓解，5年未观察到疾病进展。根治性放疗对直肠MALT淋巴瘤有效。
