Fahs Christopher A, Thiebaud Robert S, Rossow Lindy M, Loenneke Jeremy P, Bemben Debra A, Bemben Michael G
Lindenwood University Belleville, Belleville, IL, USA.
Texas Wesleyan University, Fort Worth, TX, USA.
Clin Physiol Funct Imaging. 2018 Jul;38(4):676-680. doi: 10.1111/cpf.12467. Epub 2017 Aug 16.
Relationships between muscular strength and arterial stiffness as well as between muscle mass and arterial stiffness have been observed suggesting a link between the neuromuscular system and vascular health. However, the relationship between central arterial stiffness and absolute and relative strength along with muscle mass has not been investigated in both sexes across a broad age range. The purpose of this study was to examine the relationship between central arterial stiffness and absolute and relative strength as well as between central arterial stiffness and lean body mass (LBM) in men and women across a broad age range. LBM, central arterial stiffness and strength were measured on 36 men and 35 women between the ages of 18 and 75 years. Strength was measured on five machine resistance exercises and summed as one measure of overall strength (absolute strength). Relative strength was calculated as total strength divided by LBM (relative strength). Central arterial stiffness was inversely related to both absolute (r = -0·230; P = 0·029) and relative strength (r = -0·484; P < 0·001) but not LBM (r = 0·097; P = 0·213). The relationship between central arterial stiffness and relative strength was attenuated but still present when controlling for either age, per cent body fat, LBM or mean arterial pressure. These results suggest that, across a wide age range, the expression of relative muscular strength has a stronger relationship with central arterial stiffness compared to either LBM or absolute strength. This suggests that muscle function more than muscle mass may be coupled with vascular health.
肌肉力量与动脉僵硬度之间以及肌肉质量与动脉僵硬度之间的关系已被观察到，这表明神经肌肉系统与血管健康之间存在联系。然而，在广泛的年龄范围内，尚未对男女两性的中心动脉僵硬度与绝对力量、相对力量以及肌肉质量之间的关系进行研究。本研究的目的是在广泛的年龄范围内，研究男性和女性的中心动脉僵硬度与绝对力量、相对力量之间的关系，以及中心动脉僵硬度与瘦体重（LBM）之间的关系。对36名男性和35名年龄在18至75岁之间的女性进行了LBM、中心动脉僵硬度和力量的测量。通过五项器械阻力运动测量力量，并将其汇总作为整体力量（绝对力量）的一项指标。相对力量计算为总力量除以LBM（相对力量）。中心动脉僵硬度与绝对力量（r = -0·230；P = 0·029）和相对力量（r = -0·484；P < 0·001）均呈负相关，但与LBM无关（r = 0·097；P = 0·213）。在控制年龄、体脂百分比、LBM或平均动脉压时，中心动脉僵硬度与相对力量之间的关系减弱，但仍然存在。这些结果表明，在广泛的年龄范围内，与LBM或绝对力量相比，相对肌肉力量的表达与中心动脉僵硬度的关系更强。这表明肌肉功能而非肌肉质量可能与血管健康相关。
