2017年美国抗逆转录病毒疗法对男性感染艾滋病毒的备孕夫妇中预防女性感染艾滋病毒的效果
Effects of Antiretroviral Therapy to Prevent HIV Transmission to Women in Couples Attempting Conception When the Man Has HIV Infection - United States, 2017.
作者信息
Brooks John T, Kawwass Jennifer F, Smith Dawn K, Kissin Dmitry M, Lampe Margaret, Haddad Lisa B, Boulet Sheree L, Jamieson Denise J
出版信息
MMWR Morb Mortal Wkly Rep. 2017 Aug 18;66(32):859-860. doi: 10.15585/mmwr.mm6632e1.
Abstract
Existing U.S. guidelines recommend that men with human immunodeficiency virus (HIV) infection should achieve virologic suppression* with effective antiretroviral therapy (ART) before attempting conception (1). Clinical studies have demonstrated that effective ART profoundly reduces the risk for HIV transmission (2-4). This information might be useful for counseling couples planning a pregnancy in which the man has HIV infection and the woman does not (i.e., a mixed HIV-status couple, often referred to as a serodiscordant couple).
摘要
美国现行指南建议，感染人类免疫缺陷病毒（HIV）的男性在尝试受孕前应通过有效的抗逆转录病毒疗法（ART）实现病毒学抑制（1）。临床研究表明，有效的ART可大幅降低HIV传播风险（2 - 4）。这一信息可能有助于为男方感染HIV而女方未感染（即HIV感染状况不同的夫妇，通常称为血清学不一致夫妇）且计划怀孕的夫妇提供咨询。
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