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身体活跃男性在β-肾上腺素能受体阻滞剂作用下进行连续和间歇性多级最大运动测试的比较。

Comparison of continuous and intermittent multistage maximal exercise testing during beta-adrenoceptor blockade in physically active men.

作者信息

Gordon N F, van Rensburg J P, Russell H M, Karolczak I, Celliers C P, Myburgh D P

出版信息

Int J Sports Med. 1987 Feb;8(1):6-10. doi: 10.1055/s-2008-1025632.

DOI:10.1055/s-2008-1025632
PMID:2881901
Abstract

Cardiorespiratory responses of 11 healthy males were studied, with placebo and propranolol, during a continuous and an intermittent multistage maximal treadmill test. With placebo, equivalent maximal heart rates were attained for the disparate test modes, and the intermittent protocol yielded a slightly higher (2%, P less than 0.01) maximal O2 consumption. In contrast, during beta-adrenoceptor blockade, higher maximal heart rates (5.1%, P less than 0.01) and O2 consumptions (4.4%, P less than 0.02) were reached with intermittent compared with continuous testing. Values were, however, markedly lower (P less than 0.001) for both protocols than with placebo. These results demonstrate that the precise degree of attenuation of maximal heart rate and O2 consumption observed in physically active persons receiving propranolol is partly dependent upon the actual test protocol utilized. Furthermore, the present data suggest an advantage for intermittent testing when accurate evaluation of the maximal cardiorespiratory capacity is desired in such individuals.

摘要

在连续和间歇多级最大运动平板试验期间,对11名健康男性在服用安慰剂和普萘洛尔时的心肺反应进行了研究。服用安慰剂时,不同测试模式下达到了同等的最大心率,且间歇方案产生了略高(2%,P<0.01)的最大耗氧量。相比之下,在β-肾上腺素能受体阻断期间,与连续测试相比,间歇测试达到了更高的最大心率(5.1%,P<0.01)和耗氧量(4.4%,P<0.02)。然而,两种方案的值均明显低于服用安慰剂时(P<0.001)。这些结果表明,在接受普萘洛尔的体力活动者中观察到的最大心率和耗氧量的精确衰减程度部分取决于所采用的实际测试方案。此外,目前的数据表明,当希望对这类个体的最大心肺能力进行准确评估时,间歇测试具有优势。

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引用本文的文献

1
Beta-adrenoceptor blockade and exercise. An update.β-肾上腺素能受体阻滞剂与运动。最新进展。
Sports Med. 1988 Apr;5(4):209-25. doi: 10.2165/00007256-198805040-00002.