Shenzhen Key Laboratory for Psychological Healthcare, Shenzhen Institute of Mental Health, Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen, Guangdong Province, China.
Affiliated Wuhan Mental Health Center (The Ninth Clinical School), Tongji Medical College of Huazhong University of Science & Technology, Wuhan, Hubei Province, China.
Sci Rep. 2017 Aug 18;7(1):8840. doi: 10.1038/s41598-017-09404-w.
To date there have been no studies investigating the characteristics of pain in Chinese heroin-dependent patients (HDPs) receiving methadone maintenance treatment (MMT). This study examined the frequency and socio-demographic and clinical correlates of pain in HDPs under MMT. A consecutive sample of 603 HDPs was recruited from three MMT clinics in Wuhan, China. These patients completed a standardized questionnaire concerning socio-demographic and clinical data. Pain intensity was assessed with the 5-point Verbal Rating Scale ("Overall, how intense is your pain now?") with responses of: 1 = none, 2 = mild, 3 = moderate, 4 = severe, 5 = very severe. A pain score of three or higher was used to denote clinical significant pain (CSP). The prevalence of CSP in HDPs receiving MMT was 53.6%. Factors significantly associated CSP in multiple logistics regression analysis were old age, marital status of "non-married", unemployment, having religious beliefs, a history of injecting heroin, a high dose of methadone, and more depressive symptoms. Over a half of Chinese HDPs receiving MMT have CSP. Services for HDPs in MMT settings should include periodic screening for pain, psychosocial supports, and professional treatment for pain.
迄今为止，尚无研究调查接受美沙酮维持治疗（MMT）的中国海洛因依赖患者（HDP）的疼痛特征。本研究调查了 MMT 下 HDP 疼痛的频率以及社会人口学和临床相关性。从中国武汉的三个 MMT 诊所连续招募了 603 名 HDP 患者。这些患者完成了一份关于社会人口学和临床数据的标准化问卷。疼痛强度使用 5 分言语评定量表（“总体而言，您现在的疼痛有多强烈？”）进行评估，回答为：1=无，2=轻度，3=中度，4=重度，5=非常严重。疼痛评分为 3 或更高表示存在临床显著疼痛（CSP）。接受 MMT 的 HDP 中 CSP 的患病率为 53.6%。多因素逻辑回归分析显示，年龄较大、“未婚”的婚姻状况、失业、有宗教信仰、有海洛因注射史、美沙酮剂量较高以及更多的抑郁症状与 CSP 显著相关。超过一半接受 MMT 的中国 HDP 存在 CSP。MMT 环境中 HDP 的服务应包括定期筛查疼痛、社会心理支持以及疼痛的专业治疗。
