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初次保留交叉韧带全膝关节置换失败后聚乙烯的线性和体积磨损模式:一项使用光学扫描和计算机辅助设计模型的分析

Linear and Volumetric Polyethylene Wear Patterns after Primary Cruciate-Retaining Total Knee Arthroplasty Failure: An Analysis Using Optical Scanning and Computer-Aided Design Models.

作者信息

Valič Matej, Milošev Ingrid, Levašič Vesna, Blas Mateja, Podovšovnik Eva, Koren Jaka, Trebše Rihard

机构信息

Valdoltra Orthopaedic Hospital, Jadranska cesta 31, 6280 Ankaran, Slovenia.

Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000 Ljubljana, Slovenia.

出版信息

Materials (Basel). 2024 Oct 13;17(20):5007. doi: 10.3390/ma17205007.

Abstract

(1) Background: Analyses of retrieved inserts allow for a better understanding of TKA failure mechanisms and the detection of factors that cause increased wear. The purpose of this implant retrieval study was to identify whether insert volumetric wear significantly differs among groups of common causes of total knee arthroplasty failure, whether there is a characteristic wear distribution pattern for a common cause of failure, and whether nominal insert size and component size ratio (femur-to-insert) influence linear and volumetric wear rates. (2) Methods: We digitally reconstructed 59 retrieved single-model cruciate-retaining inserts and computed their articular load-bearing surface wear utilizing an optical scanner and computer-aided design models as references. After comprehensively reviewing all cases, each was categorized into one or more of the following groups: prosthetic joint infection, osteolysis, clinical loosening of the component, joint malalignment or component malposition, instability, and other isolated causes. The associations between volumetric wear and causes of failure were estimated using a multiple linear regression model adjusted for time in situ. Insert linear penetration wear maps from the respective groups of failure were further processed and merged to create a single average binary image, highlighting a potential wear distribution pattern. The differences in wear rates according to nominal insert size (small vs. medium vs. large) and component size ratio (≤1 vs. >1) were tested using the Kruskal-Wallis test and the Mann-Whitney test, respectively. (3) Results: Patients with identified osteolysis alone and those also with clinical loosening of the component had significantly higher volumetric wear when compared to those without both causes ( = 0.016 and = 0.009, respectively). All other causes were not significantly associated with volumetric wear. The instability group differentiated from the others with a combined peripheral antero-posterior wear distribution. Linear and volumetric wear rates showed no significant differences when compared by nominal insert size (small vs. medium vs. large, = 0.563 and = 0.747, respectively) or by component (femoral-to-insert) size ratio (≤1 vs. >1, = 0.885 and = 0.055, respectively). (4) Conclusions: The study found increased volumetric wear in cases of osteolysis alone, with greater wear when combined with clinical loosening compared to other groups. The instability group demonstrated a characteristic peripheral anterior and posterior wear pattern. Insert size and component size ratio seem not to influence wear rates.

摘要

(1) 背景:对取出的植入物进行分析有助于更好地理解全膝关节置换术(TKA)的失败机制,并检测导致磨损增加的因素。本植入物取出研究的目的是确定在全膝关节置换术失败的常见原因组中,植入物的体积磨损是否存在显著差异,一种常见失败原因是否存在特征性的磨损分布模式,以及标称植入物尺寸和部件尺寸比(股骨与植入物)是否会影响线性磨损率和体积磨损率。(2) 方法:我们对59个取出的单模型保留交叉韧带的植入物进行了数字重建,并利用光学扫描仪和计算机辅助设计模型作为参考来计算其关节承重表面的磨损。在全面审查所有病例后,将每个病例归类为以下一个或多个组:人工关节感染、骨溶解、部件临床松动、关节排列不齐或部件位置不当、不稳定以及其他孤立原因。使用针对在位时间进行调整的多元线性回归模型来估计体积磨损与失败原因之间的关联。对各个失败组的植入物线性穿透磨损图进行进一步处理并合并,以创建一个单一的平均二值图像,突出显示潜在的磨损分布模式。分别使用Kruskal-Wallis检验和Mann-Whitney检验来测试根据标称植入物尺寸(小、中、大)和部件尺寸比(≤1与>1)的磨损率差异。(3) 结果:与没有这两种原因的患者相比,仅确定有骨溶解的患者以及同时伴有部件临床松动的患者的体积磨损显著更高(分别为P = 0.016和P = 0.009)。所有其他原因与体积磨损均无显著关联。不稳定组与其他组的区别在于其前后联合的周边磨损分布。按标称植入物尺寸(小、中、大,分别为P = 0.563和P = 0.747)或按部件(股骨与植入物)尺寸比(≤1与>1,分别为P = 0.885和P = 0.055)比较时,线性磨损率和体积磨损率均无显著差异。(4) 结论:该研究发现,仅骨溶解病例的体积磨损增加,与其他组相比,合并临床松动时磨损更大。不稳定组表现出特征性的周边前后磨损模式。植入物尺寸和部件尺寸比似乎不影响磨损率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f819/11509131/72e31ba779f5/materials-17-05007-g001.jpg

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