State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu 730000, Peoples Republic of China.
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu 730000, Peoples Republic of China.
J Hazard Mater. 2018 Jan 15;342:10-19. doi: 10.1016/j.jhazmat.2017.08.009. Epub 2017 Aug 7.
Two highly sensitive probes bearing a nucleophilic imine moiety have been utilized for the selective detection of chemical warfare agent (CWA) mimics. Diethyl chlorophosphate (DCP) was used as mimic CWAs. Both iminocoumarin-benzothiazole-based probes not only demonstrated a remarkable fluorescence ON-OFF response and good recognition, but also exhibited fast response times (10s) along with color changes upon addition of DCP. Limits of detection for the two sensors 1 and 2 were calculated as 0.065μM and 0.21μM, respectively, which are much lower than most other reported probes. These two probes not only show high sensitivity and selectivity in solution, but can also be applied for the recognition of DCP in the gas state, with significant color changes easily observed by the naked eye.
两种带有亲核亚胺部分的高灵敏探针已被用于选择性检测化学战剂（CWA）模拟物。二乙基磷酰氯（DCP）被用作模拟 CWA。基于亚胺香豆素-苯并噻唑的两种探针不仅表现出显著的荧光 ON-OFF 响应和良好的识别能力，而且在加入 DCP 后还表现出快速的响应时间（10s）和颜色变化。两个传感器 1 和 2 的检测限分别计算为 0.065μM 和 0.21μM，远低于大多数其他报道的探针。这两种探针不仅在溶液中表现出高灵敏度和选择性，而且还可用于识别气态 DCP，肉眼可轻松观察到明显的颜色变化。
