From the Department of Ophthalmology, Section of Academic Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, United Kingdom.
From the Department of Ophthalmology, Section of Academic Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, United Kingdom.
J Cataract Refract Surg. 2017 Jul;43(7):980-984. doi: 10.1016/j.jcrs.2017.07.001.
We report a consecutive case series of 4 eyes in which recalcitrant epithelial ingrowth after laser in situ keratomileusis was treated with flap lift, mechanical debridement of epithelial ingrowth, sequential application of alcohol 70.0% and mitomycin-C (MMC) 0.02% to residual epithelium and across the stromal bed and underside of the flap. Secure flap apposition was achieved with the use of fibrin glue. Clinically significant epithelial ingrowth did not recur in any eye; visual acuity improved in all cases. No complications were associated with this treatment. Mechanical debridement of epithelial ingrowth with additional application of alcohol 70.0% and MMC 0.02% along with tissue glue use for flap closure appears to be a safe and effective treatment for recalcitrant cases of clinically significant epithelial ingrowth.
我们报告了 4 只眼的连续病例系列，其中激光原位角膜磨镶术后顽固的上皮内生长通过瓣掀起术、上皮内生长的机械性清创术、70.0%酒精和丝裂霉素 C（MMC）0.02%在残余上皮和基质床及瓣下的顺序应用来治疗。使用纤维蛋白胶实现了安全的瓣贴合。在任何一只眼中均未出现临床显著的上皮内生长复发；所有病例的视力均有所提高。这种治疗方法没有任何并发症。上皮内生长的机械性清创术，外加 70.0%酒精和 MMC 0.02%的应用，以及组织胶用于瓣关闭，似乎是治疗顽固的临床显著上皮内生长的一种安全有效的方法。
