Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, No.19, Xinjiekouwai Street, Beijing 100875, China.
College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin 300384, China.
Molecules. 2017 Aug 20;22(8):1379. doi: 10.3390/molecules22081379.
Sixteen compounds were isolated from the leaves and stems of Huang. Based on the NMR and MS spectral results, the structures were determined. It was confirmed that the isolated compounds included three new compounds (, and ) and one new natural product (), which were identified asmurratetra A (), murratetra B (), murratetra C () and [2-(7-methoxy-2-oxochromen-8-yl)-3-methylbut-2-enyl]3-methylbut-2-enoate (), respectively. Meanwhile, the repellent activity against was investigated for 13 of these isolated compounds. The results showed that the tested compounds had various levels of repellent activity against . Among them, compounds (4(15)-eudesmene-1β,6α-diol), (isoferulic acid) and (2,3-dihydroxypropyl hexadecanoate) showed fair repellent activity against . They might be considered as potential leading compounds for the development of natural repellents.
从黄杨叶和茎中分离得到了 16 种化合物。根据 NMR 和 MS 光谱结果，确定了其结构。证实分离得到的化合物包括 3 种新化合物（、和）和 1 种新天然产物（），分别鉴定为 murratetra A（）、murratetra B（）、murratetra C（）和[2-(7-甲氧基-2-氧代色满-8-基）-3-甲基丁-2-烯基]3-甲基丁-2-烯酸酯（）。同时，对这 13 种分离得到的化合物进行了对 的驱避活性测试。结果表明，测试化合物对 表现出不同程度的驱避活性。其中，化合物（4(15)-eudesmene-1β,6α-diol）、（异阿魏酸）和（2,3-二羟丙基十六烷酸酯）对 表现出良好的驱避活性。它们可能被认为是开发天然驱避剂的潜在先导化合物。
