Moding Magnus, Ohlsson Bodil
a Department of Internal Medicine , Lund University, Skåne University Hospital , Malmö , Sweden.
Scand J Gastroenterol. 2017 Nov;52(11):1224-1234. doi: 10.1080/00365521.2017.1365931. Epub 2017 Aug 21.
The pathophysiology behind functional gastrointestinal disease (FGID) has not been defined, but an intestinal accumulation of fermentable short-chain carbohydrates (FODMAPs) is thought to be involved. A restricted coffee intake is recommended. The aim was to investigate if symptoms of FGID were associated with intake of certain foods (including FODMAPs), as well as beverages (including coffee and tea).
Data were used from participants, age range 45-75 years, who had answered the EpiHealth questionnaire about their background factors, health status and intake of food and beverages. After exclusion of organic bowel diseases, 16,840 participants remained. The impact of food and beverages on functional abdominal pain, functional bloating, functional constipation and functional diarrhea were examined by adjusted binary logistic regression.
Wholemeal bread (Swedish cracker) (OR: 1.361; 95% CI: 1.001-1.851) and white bread (low fiber content) (OR: 1.527; 95% CI: 1.075-2.169) were associated with constipation, whereas soft wholemeal bread (high fiber content) was associated with diarrhea (OR: 1.601; 95% CI: 1.040-2.463). Cheese was associated with bloating (OR: 1.460; 95% CI: 1.004-2.123). A high tea intake was associated with abdominal pain (p for trend =.003), bloating (p for trend = .039) and diarrhea (p for trend <.001), whereas coffee intake was associated with a decreased risk of abdominal pain (p for trend = .002) and bloating (p for trend = .007). High soda intake associated with abdominal pain and bloating and juice with diarrhea.
There are weak associations between intake of grain and dairy products and FGID symptoms. Tea is associated with increased risks, whereas coffee is associated with lower risks, of FGID symptoms.
功能性胃肠病（FGID）背后的病理生理学尚未明确，但肠道中可发酵短链碳水化合物（FODMAPs）的蓄积被认为与之有关。建议限制咖啡摄入量。本研究旨在调查FGID症状是否与某些食物（包括FODMAPs）以及饮料（包括咖啡和茶）的摄入有关。
使用年龄在45 - 75岁参与者的数据，这些参与者回答了关于其背景因素、健康状况以及食物和饮料摄入情况的EpiHealth问卷。排除器质性肠道疾病后，剩余16840名参与者。通过调整后的二元逻辑回归分析食物和饮料对功能性腹痛、功能性腹胀、功能性便秘和功能性腹泻的影响。
全麦面包（瑞典薄脆饼干）（比值比：1.361；95%置信区间：1.001 - 1.851）和白面包（低纤维含量）（比值比：1.527；95%置信区间：1.075 - 2.169）与便秘有关，而软质全麦面包（高纤维含量）与腹泻有关（比值比：1.601；95%置信区间：1.040 - 2.463）。奶酪与腹胀有关（比值比：1.460；95%置信区间：1.004 - 2.123）。高茶摄入量与腹痛（趋势p值 = 0.003）、腹胀（趋势p值 = 0.039）和腹泻（趋势p值 < 0.001）有关，而咖啡摄入量与腹痛风险降低（趋势p值 = 0.002）和腹胀风险降低（趋势p值 = 0.007）有关。高苏打水摄入量与腹痛和腹胀有关，果汁与腹泻有关。
谷物和乳制品的摄入与FGID症状之间存在较弱的关联。茶与FGID症状风险增加有关，而咖啡与FGID症状风险降低有关。
