溴氰菊酯和四溴菊酯对蟑螂（美洲大蠊）中枢神经系统胆碱能突触传递的作用。
Actions of deltamethrin and tralomethrin on cholinergic synaptic transmission in the central nervous system of the cockroach (Periplaneta americana).
作者信息
Hue B, Mony L
出版信息
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987;86(2):349-52. doi: 10.1016/0742-8413(87)90092-2.
PMID:2882930
Abstract
Deltamethrin (RU 22974) and tralomethrin isomers (RU 24784 and RU 24785) block transmission at the cercal-afferent giant-interneuron synapses of the cockroach, when bath-applied to the desheathed ganglion at micromolar concentrations. The time-course of the events leading to the blockage suggests two possible target sites: one located presynaptically and the other situated on postsynaptic membranes.
摘要
当以微摩尔浓度浴加于去鞘神经节时，溴氰菊酯（RU 22974）和四氟菊酯异构体（RU 24784和RU 24785）会阻断蟑螂尾须传入巨中间神经元突触处的传递。导致阻断的事件的时间进程提示了两个可能的靶点：一个位于突触前，另一个位于突触后膜上。
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