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本文引用的文献

1
Water equivalent path length calculations using scatter-corrected head and neck CBCT images to evaluate patients for adaptive proton therapy.使用散射校正的头部和颈部CBCT图像进行水等效路径长度计算,以评估患者是否适合进行自适应质子治疗。
Phys Med Biol. 2017 Jan 7;62(1):59-72. doi: 10.1088/1361-6560/62/1/59. Epub 2016 Dec 14.
2
The rotate-plus-shift C-arm trajectory. Part I. Complete data with less than 180° rotation.旋转加平移C型臂轨迹。第一部分。旋转角度小于180°的完整数据。
Med Phys. 2016 May;43(5):2295. doi: 10.1118/1.4944785.
3
Feasibility of automated proton therapy plan adaptation for head and neck tumors using cone beam CT images.使用锥形束CT图像对头颈部肿瘤进行自动质子治疗计划调整的可行性。
Radiat Oncol. 2016 Apr 30;11:64. doi: 10.1186/s13014-016-0641-7.
4
First Clinical Investigation of Cone Beam Computed Tomography and Deformable Registration for Adaptive Proton Therapy for Lung Cancer.首次临床研究:锥形束计算机断层扫描和形变配准在肺癌自适应质子治疗中的应用。
Int J Radiat Oncol Biol Phys. 2016 May 1;95(1):549-559. doi: 10.1016/j.ijrobp.2016.01.055. Epub 2016 Feb 4.
5
Quantitative assessment of anatomical change using a virtual proton depth radiograph for adaptive head and neck proton therapy.使用虚拟质子深度射线照片对解剖结构变化进行定量评估以实现自适应头颈质子治疗。
J Appl Clin Med Phys. 2016 Mar 8;17(2):427-440. doi: 10.1120/jacmp.v17i2.5819.
6
Imaging in particle therapy: State of the art and future perspective.粒子治疗中的成像:现状与未来展望。
Acta Oncol. 2015;54(9):1254-8. doi: 10.3109/0284186X.2015.1075665. Epub 2015 Sep 2.
7
Investigating CT to CBCT image registration for head and neck proton therapy as a tool for daily dose recalculation.研究用于头颈部质子治疗的CT到CBCT图像配准,作为每日剂量重新计算的工具。
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9
C-arm cone-beam computed tomography in interventional oncology: technical aspects and clinical applications.介入肿瘤学中的C形臂锥形束计算机断层扫描:技术要点与临床应用
Radiol Med. 2014 Jul;119(7):521-32. doi: 10.1007/s11547-014-0429-5. Epub 2014 Jul 11.
10
Applications of linac-mounted kilovoltage Cone-beam Computed Tomography in modern radiation therapy: A review.直线加速器安装的千伏级锥形束计算机断层扫描在现代放射治疗中的应用:综述
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一种用于图像引导质子治疗的机器人C型臂锥束CT系统:设计与性能

A robotic C-arm cone beam CT system for image-guided proton therapy: design and performance.

作者信息

Hua Chiaho, Yao Weiguang, Kidani Takao, Tomida Kazuo, Ozawa Saori, Nishimura Takenori, Fujisawa Tatsuya, Shinagawa Ryousuke, Merchant Thomas E

机构信息

1 Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.

2 Proton Therapy Systems Design Department, Hitachi Ltd, Hitachi-shi, Japan.

出版信息

Br J Radiol. 2017 Nov;90(1079):20170266. doi: 10.1259/bjr.20170266. Epub 2017 Oct 9.

DOI:10.1259/bjr.20170266
PMID:28830239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5963391/
Abstract

OBJECTIVE

A ceiling-mounted robotic C-arm cone beam CT (CBCT) system was developed for use with a 190° proton gantry system and a 6-degree-of-freedom robotic patient positioner. We report on the mechanical design, system accuracy, image quality, image guidance accuracy, imaging dose, workflow, safety and collision-avoidance.

METHODS

The robotic CBCT system couples a rotating C-ring to the C-arm concentrically with a kV X-ray tube and a flat-panel imager mounted to the C-ring. CBCT images are acquired with flex correction and maximally 360° rotation for a 53 cm field of view. The system was designed for clinical use with three imaging locations. Anthropomorphic phantoms were imaged to evaluate the image guidance accuracy.

RESULTS

The position accuracy and repeatability of the robotic C-arm was high (<0.5 mm), as measured with a high-accuracy laser tracker. The isocentric accuracy of the C-ring rotation was within 0.7 mm. The coincidence of CBCT imaging and radiation isocentre was better than 1 mm. The average image guidance accuracy was within 1 mm and 1° for the anthropomorphic phantoms tested. Daily volumetric imaging for proton patient positioning was specified for routine clinical practice.

CONCLUSION

Our novel gantry-independent robotic CBCT system provides high-accuracy volumetric image guidance for proton therapy. Advances in knowledge: Ceiling-mounted robotic CBCT provides a viable option than CT on-rails for partial gantry and fixed-beam proton systems with the added advantage of acquiring images at the treatment isocentre.

摘要

目的

开发一种天花板安装式机器人C形臂锥束CT(CBCT)系统,用于与190°质子龙门系统和六自由度机器人患者定位器配合使用。我们报告其机械设计、系统精度、图像质量、图像引导精度、成像剂量、工作流程、安全性和防撞功能。

方法

该机器人CBCT系统将一个旋转的C形环与C形臂同心耦合,C形环上安装有kV X射线管和平板成像器。CBCT图像通过柔性校正采集,在53厘米视野下最大旋转360°。该系统设计用于三个成像位置的临床使用。使用人体模型成像以评估图像引导精度。

结果

使用高精度激光跟踪仪测量,机器人C形臂的位置精度和重复性很高(<0.5毫米)。C形环旋转的等中心精度在0.7毫米以内。CBCT成像与放射等中心的重合度优于1毫米。对于测试的人体模型,平均图像引导精度在1毫米和1°以内。为常规临床实践规定了用于质子患者定位的每日容积成像。

结论

我们新型的独立于龙门的机器人CBCT系统为质子治疗提供了高精度的容积图像引导。知识进展:天花板安装式机器人CBCT为部分龙门和固定束质子系统提供了一种比CT导轨更可行的选择,其额外优势是可在治疗等中心采集图像。