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原发性胃伯基特淋巴瘤:危及生命的呕血的罕见病因。

Primary gastric Burkitt lymphoma: a rare cause of life-threatening haematemesis.

作者信息

Ayoub Fares, Forde Justin J, Patel Niraj, Markham Merry

机构信息

Department of Medicine, University of Florida, Gainesville, Florida, USA.

Division of Hematology and Oncology, Department of Medicine, University of Florida, Gainesville, Florida, USA.

出版信息

BMJ Case Rep. 2017 Aug 22;2017:bcr-2017-220313. doi: 10.1136/bcr-2017-220313.

Abstract

Lymphomas are the second most common gastric malignancy following gastric adenocarcinoma. The majority of gastric lymphomas are either mucosa-associated lymphoid tissue lymphomas or diffuse large B-cell lymphomas. Primary gastric Burkitt lymphoma is a subtype of non-Hodgkin's lymphoma and represents an aggressive and rare malignancy with only a small number of cases reported worldwide. Clinical and radiological presentation is non-specific and mimics other gastric lymphomas. Diagnosis is established with pathological evaluation. Due to the paucity of cases, treatment of this condition is not well studied and is extrapolated from paediatric and adult literature of Burkitt lymphoma not isolated to the stomach. We present the case of a male patient with primary gastric Burkitt lymphoma who initially presented with life-threatening haematemesis, later achieving complete remission with treatment. We discuss the epidemiology, presentation and management of gastric Burkitt lymphoma.

摘要

淋巴瘤是继胃腺癌之后第二常见的胃恶性肿瘤。大多数胃淋巴瘤要么是黏膜相关淋巴组织淋巴瘤,要么是弥漫性大B细胞淋巴瘤。原发性胃伯基特淋巴瘤是非霍奇金淋巴瘤的一种亚型,是一种侵袭性且罕见的恶性肿瘤,全球仅报道了少数病例。临床和影像学表现无特异性,与其他胃淋巴瘤相似。通过病理评估确诊。由于病例稀少,对这种疾病的治疗研究不足,是从非局限于胃部的伯基特淋巴瘤的儿科和成人文献中推断而来的。我们报告了一例原发性胃伯基特淋巴瘤男性患者,该患者最初因危及生命的呕血就诊,后来经治疗实现了完全缓解。我们讨论了胃伯基特淋巴瘤的流行病学、表现和管理。

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本文引用的文献

1
Primary Gastric Burkitt's Lymphoma.原发性胃伯基特淋巴瘤
Rare Tumors. 2014 Nov 10;6(4):5300. doi: 10.4081/rt.2014.5300. eCollection 2014 Oct 27.
2
Low-intensity therapy in adults with Burkitt's lymphoma.成人伯基特淋巴瘤的低强度治疗。
N Engl J Med. 2013 Nov 14;369(20):1915-25. doi: 10.1056/NEJMoa1308392.
9
Adult Burkitt leukemia and lymphoma.成人伯基特白血病和淋巴瘤。
Blood. 2004 Nov 15;104(10):3009-20. doi: 10.1182/blood-2004-02-0405. Epub 2004 Jul 20.

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