Helm G, Batra S, Owman C
Int J Fertil. 1987 Mar-Apr;32(2):162-6.
Progesterone (P) binding sites in the ampullary and isthmic regions of the fallopian tube and corpus myometrium were measured during the follicular, ovulatory, and luteal phases. Both cytosolic and nuclear fractions were used for P receptor determination. The concentrations of P receptors were similar in the isthmus and myometrium in all three phases. Although the absolute concentration of nuclear P receptor was always lower than that of the cytosolic receptor, the overall pattern of receptor concentration in the different regions was the same, being highest in the ampulla. Both cytosolic and nuclear receptor concentrations in all tissues were lowest in the luteal phase and highest in the ovulatory phase. In all tissues examined in the luteal phase the cytosolic P receptor but not the nuclear receptor was inversely related to plasma P concentration. The data are compatible with a dual control of P receptors by estrogen and P.
在卵泡期、排卵期和黄体期，对输卵管壶腹部和峡部以及子宫肌层中的孕酮（P）结合位点进行了测量。胞质和核部分均用于孕酮受体的测定。在所有三个阶段中，峡部和子宫肌层中的孕酮受体浓度相似。尽管核孕酮受体的绝对浓度始终低于胞质受体，但不同区域受体浓度的总体模式相同，在壶腹部最高。所有组织中的胞质和核受体浓度在黄体期最低，在排卵期最高。在黄体期检查的所有组织中，胞质孕酮受体而非核受体与血浆孕酮浓度呈负相关。这些数据与雌激素和孕酮对孕酮受体的双重调控相符。
