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2型糖尿病患者禁食期间胰岛素剂量调整的共识

Consensus on Insulin Dose Modification During Fasting in Type 2 Diabetes.

作者信息

Unnikrishnan A G, Lodha Sailesh, Sharma S K

机构信息

Chief Endocrinologist and CEO, Chellaram Diabetes Institute, Pune, Maharashtra.

Consultant Endocrinologist, Fortis Escorts Hospital , Jaipur, Rajasthan.

出版信息

J Assoc Physicians India. 2017 Mar;65(3 Suppl):7-15.

Abstract

INTRODUCTION

Fasting for patients with type 2 diabetes mellitus (T2DM) carries a risk of an assortment of complications. The decision of T2DM patient to fast should be made after sufficient discussion with physician regarding the risks involved. The current consensus is developed to help physicians manage T2DM patients during fasting.

OBJECTIVE

To provide simple and easily implementable guidelines on insulin dose modification during fasting in T2DM patients.

METHODS

The expert group committee discussed and proposed six recommendations for the use of insulin regimens during fasting. The recommendations were proposed on diet, exercise and categorization of risks during fast, breaking fast, dose modification of basal insulins, premix insulins and prandial insulins. All these recommendations were based on established guidelines and published scientific literature. These evidences were then factored into the national context based on the expert committee representative's patient-physician experience in their clinical practice and common therapeutic practices followed in India to successfully achieve optimal glucose control. The final consensus-based recommendations were proposed and collectively recorded for each insulin regimen.

RESULTS

Recommendations based on insulin dose modification during fasting in T2DM patients has been developed. Patients with diabetes, who fast are recommended to keep themselves hydrated, consume low glycaemic and high fibre food but, avoid sugary and caffeinated drinks along with fried foods. The main goal of insulin therapy during fasting is to provide adequate insulin to prevent post meal hyperglycaemia and prevent hypoglycaemia during fast.

CONCLUSIONS

We hope that the consensus based recommendations mentioned in this paper will be a useful reference tool for health care practitioners to initiate and intensify insulin therapy in T2DM patients in order to successfully complete fasting without much complication.

摘要

引言

2型糖尿病(T2DM)患者禁食存在一系列并发症风险。T2DM患者是否禁食的决定应在与医生充分讨论相关风险后做出。制定本共识旨在帮助医生在禁食期间管理T2DM患者。

目的

为T2DM患者禁食期间胰岛素剂量调整提供简单且易于实施的指南。

方法

专家组委员会讨论并提出了六项关于禁食期间胰岛素治疗方案使用的建议。这些建议涉及饮食、运动、禁食期间风险分类、开斋、基础胰岛素、预混胰岛素和餐时胰岛素的剂量调整。所有这些建议均基于既定指南和已发表的科学文献。然后,根据专家委员会代表在临床实践中的医患经验以及印度普遍遵循的治疗方法,将这些证据纳入本国实际情况,以成功实现最佳血糖控制。针对每种胰岛素治疗方案,提出并共同记录了基于最终共识的建议。

结果

已制定出T2DM患者禁食期间胰岛素剂量调整的建议。建议禁食的糖尿病患者保持水分充足,食用低血糖生成指数和高纤维食物,但要避免含糖和含咖啡因的饮料以及油炸食品。禁食期间胰岛素治疗的主要目标是提供足够的胰岛素以预防餐后高血糖,并防止禁食期间低血糖。

结论

我们希望本文提及的基于共识的建议将成为医疗保健从业者在T2DM患者中启动和强化胰岛素治疗的有用参考工具,以便成功完成禁食且无过多并发症。

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