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医院内多重耐药鲍曼不动杆菌暴发:空气传播模式?

Hospital outbreak of multi-resistant Acinetobacter anitratus: an airborne mode of spread?

作者信息

Allen K D, Green H T

出版信息

J Hosp Infect. 1987 Mar;9(2):110-9. doi: 10.1016/0195-6701(87)90048-x.

DOI:10.1016/0195-6701(87)90048-x
PMID:2883217
Abstract

During a 10-month period, from October 1984 to July 1985, a multi-resistant strain of Acinetobacter anitratus was isolated from 36 patients in three neurosurgical wards, one medical ward and the intensive care unit of a district general hospital, and from two patients in the intensive care unit of a hospital in another district. Fourteen patients developed significant infection including pneumonia (10), meningitis (2), septicaemia (2) and wound infection (4). The majority of cases (28) involved the respiratory tract of ventilated patients, although respiratory equipment was not implicated as a source of the infection. The epidemic strain was recovered from the skin, nose, mouth and rectum of colonized patients and from the hands of personnel. However, extensive air and environmental contamination in the vicinity of colonized patients was also demonstrated. This is the first outbreak of infection with Acinetobacter, of which we are aware, where airborne spread has been observed.

摘要

在1984年10月至1985年7月这10个月期间,在一家地区综合医院的三个神经外科病房、一个内科病房和重症监护病房的36名患者中,以及在另一个地区一家医院的重症监护病房的两名患者中,分离出了一株多重耐药的鲍曼不动杆菌。14名患者发生了严重感染,包括肺炎(10例)、脑膜炎(2例)、败血症(2例)和伤口感染(4例)。大多数病例(28例)累及接受机械通气患者的呼吸道,尽管未发现呼吸设备是感染源。在定植患者的皮肤、鼻腔、口腔和直肠以及医护人员的手上均分离出了流行菌株。然而,也证实了在定植患者附近存在广泛的空气和环境污染。据我们所知,这是首次观察到通过空气传播的鲍曼不动杆菌感染暴发。

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