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巴西普通重症监护病房中的心肺复苏:我们应该做得更少还是更好?

Cardiopulmonary Resuscitation in an Average Brazilian Intensive Care Unit: Should We Perform Less or Better?

作者信息

Miana Leonardo Augusto, Moraes Marcella Mendes, Moraes Bernardo Mendes, Ponte Pedro Guilherme, Venturelli Eduardo, Mallosto Rodrigo Urbano, Moreira-Almeida Alexander

机构信息

Faculdade de Medicina da Universidade Federal de Juiz de Fora (FAMED-UFJF), Juiz de Fora, MG, Brazil.

Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (InCor HC-FMUSP), São Paulo, SP, Brazil.

出版信息

Braz J Cardiovasc Surg. 2017 May-Jun;32(3):177-183. doi: 10.21470/1678-9741-2017-0036.

Abstract

INTRODUCTION

: Few data can be found about cardiac arrest in the intensive care unit outside reference centers in third world countries.

OBJECTIVE

: To study epidemiology and prognostic factors associated with cardiac arrest in the intensive care unit (ICU) in an average Brazilian center.

METHODS

: Between June 2011 and July 2014, 302 cases of cardiac arrest in the intensive care unit were prospectively evaluated in 273 patients (age: 68.9 ± 15 years) admitted in three mixed units. Data regarding cardiac arrest and cardiopulmonary resuscitation were collected in an "Utstein style" form and epidemiologic data was prospectively obtained. Factors associated with do not resuscitate orders, return of spontaneous circulation and survival were studied using binary logistic regression. Statistical package software used was SPSS 19.0 (IBM Inc., USA).

RESULTS

: Among 302 cardiac arrests, 230 (76.3%) had their initial rhythm recorded and 141 (61.3%) was in asystole, 62 (27%) in pulseless electric activity (PEA) and 27 had a shockable rhythm (11.7%). In 109 (36.1%) cases, cardiac arrest had a suspected reversible cause. Most frequent suspected cardiac arrest causes were hypotension (n=98; 32.5%), multiple (19.2%) and hypoxemia (17.5%). Sixty (19.9%) cardiac arrests had do not resuscitate orders. Prior left ventricle dysfunction was the only predictor of do not resuscitate order (OR: 3.1 [CI=1.03-9.4]; P=0.04). Among patients that received cardiopulmonary resuscitation, 59 (24.4%) achieved return of spontaneous circulation and 12 survived to discharge (5.6%). Initial shockable rhythm was the only return of spontaneous circulation predictor (OR: 24.9 (2.4-257); P=0.007) and survival (OR: 4.6 (1.4-15); P=0.01).

CONCLUSION

: Cardiopulmonary resuscitation rate was high considering ICU patients, so was mortality. Prior left ventricular dysfunction was a predictor of do not resuscitate order. Initial shockable rhythm was a predictor of return of spontaneous circulation and survival.

摘要

引言

在第三世界国家,除了参考中心外,关于重症监护病房心脏骤停的数据很少。

目的

研究巴西一个普通中心重症监护病房(ICU)心脏骤停的流行病学及相关预后因素。

方法

2011年6月至2014年7月期间,对三个混合病房收治的273例患者(年龄:68.9±15岁)发生的302例重症监护病房心脏骤停进行了前瞻性评估。以“乌斯坦样式”表格收集心脏骤停及心肺复苏的数据,并前瞻性获取流行病学数据。使用二元逻辑回归研究与不进行心肺复苏医嘱、自主循环恢复及生存相关的因素。使用的统计软件包为SPSS 19.0(美国IBM公司)。

结果

在302例心脏骤停中,230例(76.3%)记录了初始心律,其中141例(61.3%)为心搏停止,62例(27%)为无脉电活动(PEA),27例有可电击心律(11.7%)。109例(36.1%)心脏骤停有疑似可逆病因。最常见的疑似心脏骤停病因是低血压(n=98;32.5%)、多种病因(19.2%)和低氧血症(17.5%)。60例(19.9%)心脏骤停有不进行心肺复苏医嘱。既往左心室功能障碍是不进行心肺复苏医嘱的唯一预测因素(比值比:3.1[可信区间=1.03 - 9.4];P=0.04)。在接受心肺复苏的患者中,59例(24.4%)实现了自主循环恢复,12例存活至出院(5.6%)。初始可电击心律是自主循环恢复的唯一预测因素(比值比:24.9(2.4 - 257);P=0.007)和生存的唯一预测因素(比值比:4.6(1.4 - 15);P=0.01)。

结论

考虑到ICU患者,心肺复苏率较高,死亡率也较高。既往左心室功能障碍是不进行心肺复苏医嘱的预测因素。初始可电击心律是自主循环恢复及生存的预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/142f/5570398/534335c4d564/rbccv-32-03-0177-g01.jpg

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