Dalgleish R, Hawkins J R, Keston M
J Med Genet. 1987 Mar;24(3):148-51. doi: 10.1136/jmg.24.3.148.
The inheritance of restriction fragment length polymorphisms for two fibrillar collagen genes (COL1A2 and COL3A1) has been studied in a large Marfan syndrome kindred. We are able to show discordant segregation between the Marfan syndrome and each of the two collagen gene markers.
在一个大型马凡氏综合征家族中,对两个纤维状胶原蛋白基因(COL1A2和COL3A1)的限制性片段长度多态性的遗传情况进行了研究。我们能够证明马凡氏综合征与这两个胶原蛋白基因标记中的每一个之间存在不一致的分离情况。