de Faria Natália S, Moura Luana K B, de Macedo Luciana M D, Colucci Vivian, Raucci-Neto Walter, Messias Danielle C
School of Dentistry, University of Ribeirão Preto, Ribeirão Preto, SP, Brazil.
Eur J Oral Sci. 2017 Oct;125(5):403-409. doi: 10.1111/eos.12368. Epub 2017 Aug 20.
The use of matrix metalloproteinase (MMPs) inhibitors, such as 12-methacryloyloxy-dodecyl-pyridinium-bromide (MDPB), might improve the adhesion of glass-fiber (GF) and polyfiber (PF) posts to root dentine. This study assessed the effect of an MDPB-containing adhesive on the long-term bond strength of GF or PF posts to bovine dentine. Bovine endodontically treated roots were randomly divided into six groups, according to the post type and adhesive system used, as follows: GF serrated post + MDBP-free adhesive; GF serrated post + MDPB-containing adhesive; GF smooth post + MDBP-free adhesive; GF smooth post + MDPB-containing adhesive; PF post + MDBP-free adhesive; PF post + MDPB-containing adhesive. Specimens were stored in water for 6 months, thermocycled (500 cycles wk ), and submitted to the pull-out test and failure pattern analysis. The cement-dentin interface was evaluated using scanning electron microscopy. The pull-out data were analyzed using anova and Tukey's test (α = 0.05). No significant interaction between the type of post and the adhesive system was found. Polyfiber posts showed lower bond strength than GF posts, whether serrated or smooth, and the bond strength of the serrated and smooth GF posts was not significantly different. Adhesive failures were predominant in all groups. The type of retainer influenced the bond strength, and MDPB-containing adhesive did not improve the long-term bond strength of posts to dentine.
使用基质金属蛋白酶（MMPs）抑制剂，如12-甲基丙烯酰氧基十二烷基溴化吡啶（MDPB），可能会改善玻璃纤维（GF）桩和聚纤维（PF）桩与牙根牙本质的黏附力。本研究评估了含MDPB的黏结剂对GF桩或PF桩与牛牙本质长期粘结强度的影响。根据所使用的桩类型和黏结剂系统，将经牙髓治疗的牛牙根随机分为六组，如下：GF锯齿桩+不含MDBP的黏结剂；GF锯齿桩+含MDPB的黏结剂；GF光滑桩+不含MDBP的黏结剂；GF光滑桩+含MDPB的黏结剂；PF桩+不含MDBP的黏结剂；PF桩+含MDPB的黏结剂。标本在水中储存6个月，进行热循环（每周500次循环），并进行拔出试验和失效模式分析。使用扫描电子显微镜评估黏固剂-牙本质界面。拔出数据采用方差分析和Tukey检验进行分析（α = 0.05）。未发现桩类型与黏结剂系统之间有显著相互作用。无论锯齿状还是光滑的，聚纤维桩的粘结强度均低于GF桩，且锯齿状和光滑GF桩的粘结强度无显著差异。所有组中粘结失败均占主导。固位体类型影响粘结强度，含MDPB的黏结剂并未提高桩与牙本质的长期粘结强度。
