Rivera Jessica V, Vance Emily Green, Rushton William F, Arnold Justin K
Departments of Pharmacy (Drs Rivera and Vance) and Emergency Medicine (Drs Rushton and Arnold), UAB Hospital, Birmingham, Alabama.
Crit Care Nurs Q. 2017 Oct/Dec;40(4):374-382. doi: 10.1097/CNQ.0000000000000174.
The purpose of this paper is to review the most common and quickest growing classes of novel, or new, psychoactive substances. Abuse of novel psychoactive substances continues to increase, resulting in subsequent increases in hospitalizations. Furthermore, the chemical structures are ever-changing and substances are increasing in potency. Reviewing the chemistry behind these agents will facilitate a better understanding of the toxicity associated with them and allow for successful identification of and management in the critical care unit. Being familiar with the most common psychoactive substances and trends of abuse, as well as the challenges health care providers face when managing intoxication, is essential to the overall understanding and care of these critically ill patients.
本文的目的是回顾新型精神活性物质中最常见且增长最快的类别。新型精神活性物质的滥用情况持续增加，导致住院人数随之上升。此外，其化学结构不断变化，物质的效力也在增强。审视这些药物背后的化学原理将有助于更好地理解与之相关的毒性，并在重症监护病房实现对它们的成功识别与管理。熟悉最常见的精神活性物质及其滥用趋势，以及医疗保健提供者在处理中毒情况时所面临的挑战，对于全面了解和护理这些重症患者至关重要。
