Tomkins A, Ahmad S, Cannon L, Higgins S P, Kliner M, Kolyva A, Ward C, Vivancos R
1 Pennine Acute Hospitals NHS Trust and Public Health England/BASHH Fellowship, Manchester, UK.
2 5295 University Hospital of South Manchester , Manchester, UK.
Int J STD AIDS. 2018 Mar;29(4):350-356. doi: 10.1177/0956462417725638. Epub 2017 Aug 23.
Recreational drug use (RDU) has been reported to be disproportionately higher in men who have sex with men (MSM) when compared to their heterosexual counterparts. To identify RDU, links to risky sexual practices and infections for MSM attending three sexual health clinics across Manchester, United Kingdom, a retrospective case note review was conducted using a random powered sample of service users attending three sites during 2014. Three hundred and fifty-seven case notes were reviewed across three sites. Eighteen per cent of service users reported any type of RDU. Use of at least one of the three drugs associated with chemsex (crystal methamphetamine, mephedrone, gamma hydroxybutyrate/gamma butyrolactone) was reported by 3.6%. A statistically significant difference was identified between non-drug users and any-drug users reporting: group sex (odds ratio [OR] 5.88, p = 0.013), condomless receptive anal intercourse (CRAI) (OR 2.77, p = 0.003) and condomless oral intercourse (OR 2.52, p = 0.016). A statistically significant difference was identified between chemsex-related drug user and non-drug user groups reporting: group sex (OR 13.05, p = 0.023), CRAI (OR 3.69, p = 0.029) and condomless insertive anal intercourse (OR 1.27, p = 0.039). There was also a statistically higher incidence of gonorrhoea infection in chemsex-related drug use compared with those not using drugs (p = 0.002, OR 6.88). This study identifies that substance use is common in MSM attending sexual health clinics in Manchester. High-risk sexual practices and certain sexually transmitted infections are more common in MSM reporting RDU.
据报道，与异性恋男性相比，男男性行为者（MSM）的消遣性药物使用（RDU）比例过高。为了确定在英国曼彻斯特三家性健康诊所就诊的男男性行为者的消遣性药物使用情况、与危险性行为及感染之间的联系，我们对2014年在三个地点就诊的服务对象进行了随机抽样，进行回顾性病例记录审查。在三个地点共审查了357份病例记录。18%的服务对象报告有任何类型的消遣性药物使用情况。报告使用了与化学性行为相关的三种药物（冰毒、甲氧麻黄酮、γ-羟基丁酸/γ-丁内酯）中至少一种的比例为3.6%。在报告有以下情况的非药物使用者和使用任何药物的使用者之间发现了统计学上的显著差异：群交（优势比[OR]5.88，p = 0.013）、无保护的接受性肛交（CRAI）（OR 2.77，p = 0.003）和无保护的口交（OR 2.52，p = 0.016）。在报告有以下情况的与化学性行为相关的药物使用者和非药物使用者群体之间发现了统计学上的显著差异：群交（OR 13.05，p = 0.023）、CRAI（OR 3.69，p = 0.029）和无保护的插入性肛交（OR 1.27，p = 0.039）。与未使用药物的人相比，与化学性行为相关的药物使用中淋病感染的发生率在统计学上也更高（p = 0.002，OR 6.88）。本研究表明，在曼彻斯特性健康诊所就诊的男男性行为者中，物质使用情况很常见。报告有消遣性药物使用的男男性行为者中，高危性行为和某些性传播感染更为常见。
