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中国煤矿工人血脂异常患病率及相关危险因素的横断面调查研究。

Prevalence of dyslipidaemia and risk factors in Chinese coal miners: a cross-sectional survey study.

机构信息

Department of Environmental Health, School of Public Health, Shanxi Medical University, 56 Xinjiannanlu Street, TaiYuan, Shanxi, 030001, China.

Department of Surgery, General Hospital of Datong Coal Mining Group, DaTong, Shanxi, China.

出版信息

Lipids Health Dis. 2017 Aug 23;16(1):161. doi: 10.1186/s12944-017-0548-9.

DOI:10.1186/s12944-017-0548-9
PMID:28835245
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5569536/
Abstract

BACKGROUND

Although coal miners are susceptible to dyslipidaemia owing to their highly risky and stressful working environment as well as unhealthy lifestyle, very few studies have focused on this issue thus far. Therefore, this study investigated the current epidemiological characteristics of dyslipidaemia among Chinese coal miners.

METHODS

Demographic, anthropometric, and biochemical data were gathered from 4341 coal miners in China. Dyslipidaemia was diagnosed based on the serum lipid levels. Univariate and multivariate logistic regression analyses were used to assess the related risk factors for dyslipidaemia.

RESULTS

The average concentrations of total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were 5.01 ± 0.93 mmol/L, 1.90 ± 1.72 mmol/L, 1.21 ± 0.35 mmol/L, and 3.15 ± 0.80 mmol/L, respectively. Additionally, 38.08% of participants had a high TC level, 25.84% had a low HDL-C level, 35.08% had a high LDL-C level, and 40.46% had a high TG level. The overall prevalence of dyslipidaemia was 68.28% (95% CI: 66.90-69.66%). Factors associated with dyslipidaemia were age, sex, marital status, monthly family income, type of work, length of service, smoking status, smoking index, drinking status, alcohol consumption per day, elevated fasting glucose, hypertension, obesity and abdominal obesity.

CONCLUSIONS

Our study's results indicated a very high prevalence of dyslipidaemia among Chinese coal miners and identified various risk factors for dyslipidaemia.

摘要

背景

由于煤矿工人工作环境风险高、压力大,以及生活方式不健康,他们容易出现血脂异常,但迄今为止,针对这一问题的研究甚少。因此,本研究调查了中国煤矿工人血脂异常的当前流行病学特征。

方法

从中国的 4341 名煤矿工人中收集人口统计学、人体测量学和生化数据。根据血清脂质水平诊断血脂异常。采用单因素和多因素 logistic 回归分析评估血脂异常的相关危险因素。

结果

总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)的平均浓度分别为 5.01±0.93mmol/L、1.90±1.72mmol/L、1.21±0.35mmol/L和 3.15±0.80mmol/L。此外,38.08%的参与者 TC 水平升高,25.84%的参与者 HDL-C 水平降低,35.08%的参与者 LDL-C 水平升高,40.46%的参与者 TG 水平升高。血脂异常的总患病率为 68.28%(95%置信区间:66.90-69.66%)。与血脂异常相关的因素有年龄、性别、婚姻状况、月家庭收入、工作类型、工龄、吸烟状况、吸烟指数、饮酒状况、每天饮酒量、空腹血糖升高、高血压、肥胖和腹型肥胖。

结论

我们的研究结果表明,中国煤矿工人血脂异常的患病率非常高,并确定了血脂异常的多种危险因素。

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